Epithelial layer fluidization by curvature-induced unjamming.
Marzio M, Das A, Fredberg JJ, Bi D.
ArXiv. 2023 May 22. PMID: 37292460
Our laboratory seeks to discover physical laws governing the abilities of the cytoskeleton to deform, contract, and remodel. These basic mechanical processes underlie a range of higher level phenomena in health and disease including many aspects of cancer, cardiovascular disease, malaria, and morphogenesis, but our major research emphasis is the role of these processes in airway narrowing in asthma. Trainees with backgrounds in engineering sciences, cell biology, or physics of soft condensed matter learn how to work side-by-side to pose new questions, invent new nanotechnologies, apply these technologies in novel experimental investigations, and analyze resulting data in terms of evolving mechanistic understanding of the physical properties of the living cell.
BSME, 1968
Tufts University, Medford, Massachusetts
PhD, 1973
Massachusetts Institute of Technology, Cambridge, Massachusetts
Marzio M, Das A, Fredberg JJ, Bi D.
ArXiv. 2023 May 22. PMID: 37292460
He S, Lei P, Kang W, Cheung P, Xu T, Mana M, Park CY, Wang H, Imada S, Russell JO, Wang J, Wang R, Zhou Z, Chetal K, Stas E, Mohad V, Bruun-Rasmussen P, Sadreyev RI, Hodin RA, Zhang Y, Breault DT, Camargo FD, Yilmaz ÖH, Fredberg JJ, Saeidi N.
Gastroenterology. 2023 06. 164(7):1137-1151.e15. PMID: 36871599
Panganiban RAM, Yang Z, Sun M, Park CY, Kasahara DI, Schaible N, Krishnan R, Kho AT, Israel E, Hershenson MB, Weiss ST, Himes BE, Fredberg JJ, Tantisira KG, Shore SA, Lu Q.
Nat Commun. 2023 01 04. 14(1):47. PMID: 36599824
Vahabikashi A, Sivagurunathan S, Nicdao FAS, Han YL, Park CY, Kittisopikul M, Wong X, Tran JR, Gundersen GG, Reddy KL, Luxton GWG, Guo M, Fredberg JJ, Zheng Y, Adam SA, Goldman RD.
Proc Natl Acad Sci U S A. 2022 04 26. 119(17):e2121816119. PMID: 35439057
Wu H, Shen Y, Sivagurunathan S, Weber MS, Adam SA, Shin JH, Fredberg JJ, Medalia O, Goldman R, Weitz DA.
Proc Natl Acad Sci U S A. 2022 03 08. 119(10):e2115217119. PMID: 35235449
Mwase C, Phung TN, O'Sullivan MJ, Mitchel JA, De Marzio M, Kiliç A, Weiss ST, Fredberg JJ, Park JA.
Cells. 2022 01 13. 11(2). PMID: 35053372
Kang W, Ferruzzi J, Spatarelu CP, Han YL, Sharma Y, Koehler SA, Mitchel JA, Khan A, Butler JP, Roblyer D, Zaman MH, Park JA, Guo M, Chen Z, Pegoraro AF, Fredberg JJ.
iScience. 2021 Nov 19. 24(11):103252. PMID: 34755092
Mohammed D, Park CY, Fredberg JJ, Weitz DA.
Sci Rep. 2021 08 11. 11(1):16279. PMID: 34381087
Atia L, Fredberg JJ, Gov NS, Pegoraro AF.
Cells Dev. 2021 Dec. 168:203727. PMID: 34363993
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