Epigenetic Clock at Birth and Childhood Blood Pressure Trajectory: A Prospective Birth Cohort Study.
Hu J, Yaskolka Meir A, Hong X, Wang G, Hu FB, Wang X, Liang L.
Hypertension. 2024 Oct. 81(10):e113-e124. PMID: 39087326
I am an Instructor in the Center for Genomic Medicine and Department of Anaesthesia at Massachusetts General Hospital and Harvard Medical School, and the Department of Epidemiology at Harvard T.H. Chan School of Public Health. I am an epidemiologist with medical training committed to conduct research on life-course epidemiology. I have rich research experience in maternal and child health, women’s health, and environmental health.
I am interested the etiology of adverse pregnancy outcomes and their long-term impact on cardiometabolic health in women and their children. My current research utilizes large-scale, multi-omics data, under the framework of systems epidemiology, to identify novel risk factors and the underlying mechanisms of adverse pregnancy outcomes and cardiometabolic diseases in women, as well as to examine the (epi)genetic and metabolic bases of the intergenerational link in cardiometabolic disease risk. My research also extends to examining the origin and mechanisms of sex and race differences in cardiometabolic disease risk. I am also leading or participating in multiple consortium metabolomics and (epi)genetics projects in the Trans-Omics for Precision Medicine (TOPMed), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), and COnsortium of METabolomics Studies (COMETS).
MD, 06/2011, Preventive Medicine
Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
PhD, 06/2016, Environmental Health; Epidemiology
School of Public Health, Huazhong University of Science and Technology, Wuhan, China
Visiting Scholar, 06/2018, Epidemiology
Department of Epidemiology, Brown University School of Public Health, Providence, RI
Postdoctoral Research Fellow, 12/2022, Women's Health; Systems epidemiology; Biostatistics
Brigham and Women’s Hospital; Mass General Hospital; Harvard T.H. Chan School of Public Health, Boston, MA
Winner, The Sandra A. Daugherty Award for Excellence in CVD or Hypertension Epidemiology
American Heart Association
Reviewers’ Choice Abstract
American Society of Human Genetics
Connors-BRI Research Recognition Award
Brigham and Women's Hospital
Early Investigator Travel Award
American Heart Association
Semifinalist, Charles J. Epstein Trainee Award for Excellence in Human Genetics Research
American Society of Human Genetics
Trudy Bush Fellowship for Cardiovascular Disease Research in Women’s Health
American Heart Association
Hu J, Yaskolka Meir A, Hong X, Wang G, Hu FB, Wang X, Liang L.
Hypertension. 2024 Oct. 81(10):e113-e124. PMID: 39087326
Breithaupt L, Holsen LM, Ji C, Hu J, Petterway F, Rosa-Caldwell M, Nilsson IAK, Thomas JJ, Williams KA, Boutin R, Slattery M, Bulik CM, Arnold SE, Lawson EA, Misra M, Eddy KT.
Biol Psychiatry Glob Open Sci. 2024 Sep. 4(5):100332. PMID: 38989135
McGee EE, Zeleznik OA, Balasubramanian R, Hu J, Rosner BA, Wactawski-Wende J, Clish CB, Avila-Pacheco J, Willett WC, Rexrode KM, Tamimi RM, Eliassen AH.
Eur J Epidemiol. 2024 Jun. 39(6):653-665. PMID: 38703248
Nogal A, Alkis T, Lee Y, Kifer D, Hu J, Murphy RA, Huang Z, Wang-Sattler R, Kastenmüler G, Linkohr B, Barrios C, Crespo M, Gieger C, Peters A, Price J, Rexrode KM, Yu B, Menni C.
Cardiovasc Res. 2023 12 30. 119(17):2743-2754. PMID: 37706562
Hu J, Xu X, Li J, Jiang Y, Hong X, Rexrode KM, Wang G, Hu FB, Zhang H, Karmaus WJ, Wang X, Liang L.
Clin Epigenetics. 2023 03 25. 15(1):51. PMID: 36966332
Jaworek T, Xu H, Gaynor BJ, Cole JW, Rannikmae K, Stanne TM, Tomppo L, Abedi V, Amouyel P, Armstrong ND, Attia J, Bell S, Benavente OR, Boncoraglio GB, Butterworth A, Carcel-Marquez J, Chen Z, Chong M, Cruchaga C, Cushman M, Danesh J, Debette S, Duggan DJ, Durda JP, Engstrom G, Enzinger C, Faul JD, Fecteau NS, Fernandez-Cadenas I, Gieger C, Giese AK, Grewal RP, Grittner U, Havulinna AS, Heitsch L, Hochberg MC, Holliday E, Hu J, Ilinca A, Irvin MR, Jackson RD, Jacob MA, Rabionet R, Jimenez-Conde J, Johnson JA, Kamatani Y, Kardia SLR, Koido M, Kubo M, Lange L, Lee JM, Lemmens R, Levi CR, Li J, Li L, Lin K, Lopez H, Luke S, Maguire J, McArdle PF, McDonough CW, Meschia JF, Metso T, Müller-Nurasyid M, O'Connor TD, O'Donnell M, Peddareddygari LR, Pera J, Perry JA, Peters A, Putaala J, Ray D, Rexrode K, Ribases M, Rosand J, Rothwell PM, Rundek T, Ryan KA, Sacco RL, Salomaa V, Sanchez-Mora C, Schmidt R, Sharma P, Slowik A, Smith JA, Smith NL, Wassertheil-Smoller S, Söderholm M, Stine OC, Strbian D, Sudlow CLM, Tatlisumak T, Terao C, Thijs V, Torres-Aguila NP, Trégouët DA, Tuladhar AM, Veldink JH, Walters RG, Weir DR, Woo D, Worrall BB, Hong CC, Ross OA, Zand R, Leeuw FE, Lindgren AG, Pare G, Anderson CD, Markus HS, Jern C, Malik R, Dichgans M, Mitchell BD, Kittner SJ.
Neurology. 2022 Oct 17. 99(16):e1738-e1754. PMID: 36240095
Hu J, Papandonatos GD, Zheng T, Braun JM, Zhang B, Liu W, Wu C, Zhou A, Liu S, Buka SL, Shi K, Xia W, Xu S, Li Y.
Eco Environ Health. 2022 Sep. 1(3):165-171. PMID: 38075601
Hu J, Yao J, Deng S, Balasubramanian R, Jiménez MC, Li J, Guo X, Cruz DE, Gao Y, Huang T, Zeleznik OA, Ngo D, Liu S, Rosal MC, Nassir R, Paynter NP, Albert CM, Tracy RP, Durda P, Liu Y, Taylor KD, Johnson WC, Sun Q, Rimm EB, Eliassen AH, Rich SS, Rotter JI, Gerszten RE, Clish CB, Rexrode KM.
Circ Res. 2022 09 16. 131(7):601-615. PMID: 36052690
Louca P, Nogal A, Moskal A, Goulding NJ, Shipley MJ, Alkis T, Lindbohm JV, Hu J, Kifer D, Wang N, Chawes B, Rexrode KM, Ben-Shlomo Y, Kivimaki M, Murphy RA, Yu B, Gunter MJ, Suhre K, Lawlor DA, Mangino M, Menni C.
Metabolites. 2022 Jun 28. 12(7). PMID: 35888725
Cruz DE, Tahir UA, Hu J, Ngo D, Chen ZZ, Robbins JM, Katz D, Balasubramanian R, Peterson B, Deng S, Benson MD, Shi X, Dailey L, Gao Y, Correa A, Wang TJ, Clish CB, Rexrode KM, Wilson JG, Gerszten RE.
JAMA Cardiol. 2022 02 01. 7(2):184-194. PMID: 34851361