Jie Hu

I am a junior faculty member in the Saxena Lab in the Center for Genomic Medicine and Department of Anaesthesia at Massachusetts General Hospital and Harvard Medical School, and the Liang Lab in the Department of Epidemiology at Harvard T.H. Chan School of Public Health. I am an epidemiologist with rich research experience in maternal and child health, women’s health, and environmental health. My long-term career goal is to become an independent researcher in the area of women’s and children’s health and cardiometabolic disease epidemiology, focusing on identifying novel risk factors, investigating the intergenerational link in disease susceptibility and the influencing factors, and examining health disparities and the underlying mechanisms to promote personalized treatment and prevention.

I am interested the etiology of adverse pregnancy outcomes and their long-term impact on cardiometabolic health in women and their children. My current research utilizes large-scale, multi-omics data, under the framework of systems epidemiology, to identify novel risk factors and the underlying mechanisms of adverse pregnancy outcomes and cardiometabolic diseases in women, as well as to examine the (epi)genetic and metabolic bases of the intergenerational link in cardiometabolic disease risk. My research also extends to examining the origin and mechanisms of sex and race differences in cardiometabolic disease risk. I am also leading or participating in multiple consortium metabolomics and (epi)genetics projects in the Trans-Omics for Precision Medicine (TOPMed), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), and COnsortium of METabolomics Studies (COMETS).