Research Fellows

Jie Hu

Postdoctoral Research Fellow

Epidemiology

jhu13@bwh.harvard.edu

Other Positions

Research Fellow in Medicine

Medicine-Brigham and Women's Hospital

Harvard Medical School


Overview

I am a postdoctoral research fellow at Brigham and Women's Hospital and Harvard T.H. Chan School of Public Health. I have a background in environmental epidemiology and have led or contributed to multiple epidemiological and epigenome-wide studies investigating environmental and behavioral risk factors related to maternal health during pregnancy, fetal growth, and human aging in several Chinese cohorts.

I am interested in women's health, sex differences, cardiometabolic disease, (epi)genetics, and integrated omics. My current research primarily focuses on the investigation of risk factors and underlying mechanisms of coronary heart disease, ischemic stroke, and type 2 diabetes. I am leading several multi-cohort projects identifying hormonal, inflammatory, metabolomic, and genetic factors related to cardiometabolic risk, using data from the Women's Health Initiative, Nurses' Health Studies, Health Professional Follow-up Study, Multi-Ethnic Study of Atherosclerosis, and UK Biobank. I am also leading, co-leading, or participating in several consortium metabolomics and epigenetics projects in the Trans-Omics for Precision Medicine (TOPMed), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), and COnsortium of METabolomics Studies (COMETS).

MD, 06/2011, Preventive Medicine
Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

PhD, 06/2016, Environmental Epidemiology
School of Public Health, Huazhong University of Science and Technology, Wuhan, China

Visiting Scholar, 06/2018, Epidemiology
Department of Epidemiology, Brown University School of Public Health, Providence, RI

Trudy Bush Fellowship for Cardiovascular Disease Research in Women’s Health
American Heart Association

Semifinalist, Charles J. Epstein Trainee Award for Excellence in Human Genetics Research
American Society of Human Genetics

Early Investigator Travel Award
American Heart Association

Connors-BRI Research Recognition Award
Brigham and Women's Hospital


Bibliography

Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies.

Qi Q, Li J, Yu B, Moon JY, Chai JC, Merino J, Hu J, Ruiz-Canela M, Rebholz C, Wang Z, Usyk M, Chen GC, Porneala BC, Wang W, Nguyen NQ, Feofanova EV, Grove ML, Wang TJ, Gerszten RE, Dupuis J, Salas-Salvadó J, Bao W, Perkins DL, Daviglus ML, Thyagarajan B, Cai J, Wang T, Manson JE, Martínez-González MA, Selvin E, Rexrode KM, Clish CB, Hu FB, Meigs JB, Knight R, Burk RD, Boerwinkle E, Kaplan RC.

Gut. 2022 06. 71(6):1095-1105. PMID: 34127525

The Mediterranean diet, plasma metabolome, and cardiovascular disease risk.

Li J, Guasch-Ferré M, Chung W, Ruiz-Canela M, Toledo E, Corella D, Bhupathiraju SN, Tobias DK, Tabung FK, Hu J, Zhao T, Turman C, Feng YA, Clish CB, Mucci L, Eliassen AH, Costenbader KH, Karlson EW, Wolpin BM, Ascherio A, Rimm EB, Manson JE, Qi L, Martínez-González MÁ, Salas-Salvadó J, Hu FB, Liang L.

Eur Heart J. 2020 07 21. 41(28):2645-2656. PMID: 32406924