Research Fellows

Jie Hu

Postdoctoral Research Fellow


Other Positions

Instructor in Anaesthesia

Anaesthesia-Massachusetts General Hospital

Harvard Medical School


I am a junior faculty member in the Saxena Lab in the Center for Genomic Medicine and Department of Anaesthesia at Massachusetts General Hospital and Harvard Medical School, and the Liang Lab in the Department of Epidemiology at Harvard T.H. Chan School of Public Health. I am an epidemiologist with rich research experience in maternal and child health, women’s health, and environmental health. My long-term career goal is to become an independent researcher in the area of women’s and children’s health and cardiometabolic disease epidemiology, focusing on identifying novel risk factors, investigating the intergenerational link in disease susceptibility and the influencing factors, and examining health disparities and the underlying mechanisms to promote personalized treatment and prevention.

I am interested the etiology of adverse pregnancy outcomes and their long-term impact on cardiometabolic health in women and their children. My current research utilizes large-scale, multi-omics data, under the framework of systems epidemiology, to identify novel risk factors and the underlying mechanisms of adverse pregnancy outcomes and cardiometabolic diseases in women, as well as to examine the (epi)genetic and metabolic bases of the intergenerational link in cardiometabolic disease risk. My research also extends to examining the origin and mechanisms of sex and race differences in cardiometabolic disease risk. I am also leading or participating in multiple consortium metabolomics and (epi)genetics projects in the Trans-Omics for Precision Medicine (TOPMed), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), and COnsortium of METabolomics Studies (COMETS).

Research Fellow, 01/2023, Epidemiology; Biostatistics
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA

Research Fellow, 01/2023, Systems epidemiology; Medicine
Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA

MD, 06/2011, Preventive Medicine
Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

PhD, 06/2016, Environmental Epidemiology
School of Public Health, Huazhong University of Science and Technology, Wuhan, China

Visiting Scholar, 06/2018, Epidemiology
Department of Epidemiology, Brown University School of Public Health, Providence, RI

Research Fellow, 06/2022, Medicine/Women's Health
Division of Women's Health, Brigham and Women's Hospital, Boston, MA

Winner, The Sandra A. Daugherty Award for Excellence in CVD or Hypertension Epidemiology2024
American Heart Association

Reviewers’ Choice Abstract2022
American Society of Human Genetics

Connors-BRI Research Recognition Award2021
Brigham and Women's Hospital

Early Investigator Travel Award2020
American Heart Association

Semifinalist, Charles J. Epstein Trainee Award for Excellence in Human Genetics Research2019
American Society of Human Genetics

Trudy Bush Fellowship for Cardiovascular Disease Research in Women’s Health2018
American Heart Association


Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.

Jaworek T, Xu H, Gaynor BJ, Cole JW, Rannikmae K, Stanne TM, Tomppo L, Abedi V, Amouyel P, Armstrong ND, Attia J, Bell S, Benavente OR, Boncoraglio GB, Butterworth A, Carcel-Marquez J, Chen Z, Chong M, Cruchaga C, Cushman M, Danesh J, Debette S, Duggan DJ, Durda JP, Engstrom G, Enzinger C, Faul JD, Fecteau NS, Fernandez-Cadenas I, Gieger C, Giese AK, Grewal RP, Grittner U, Havulinna AS, Heitsch L, Hochberg MC, Holliday E, Hu J, Ilinca A, Irvin MR, Jackson RD, Jacob MA, Rabionet R, Jimenez-Conde J, Johnson JA, Kamatani Y, Kardia SLR, Koido M, Kubo M, Lange L, Lee JM, Lemmens R, Levi CR, Li J, Li L, Lin K, Lopez H, Luke S, Maguire J, McArdle PF, McDonough CW, Meschia JF, Metso T, Müller-Nurasyid M, O'Connor TD, O'Donnell M, Peddareddygari LR, Pera J, Perry JA, Peters A, Putaala J, Ray D, Rexrode K, Ribases M, Rosand J, Rothwell PM, Rundek T, Ryan KA, Sacco RL, Salomaa V, Sanchez-Mora C, Schmidt R, Sharma P, Slowik A, Smith JA, Smith NL, Wassertheil-Smoller S, Söderholm M, Stine OC, Strbian D, Sudlow CLM, Tatlisumak T, Terao C, Thijs V, Torres-Aguila NP, Trégouët DA, Tuladhar AM, Veldink JH, Walters RG, Weir DR, Woo D, Worrall BB, Hong CC, Ross OA, Zand R, Leeuw FE, Lindgren AG, Pare G, Anderson CD, Markus HS, Jern C, Malik R, Dichgans M, Mitchell BD, Kittner SJ.

Neurology. 2022 Oct 17. 99(16):e1738-e1754. PMID: 36240095

Differences in Metabolomic Profiles Between Black and White Women and Risk of Coronary Heart Disease: an Observational Study of Women From Four US Cohorts.

Hu J, Yao J, Deng S, Balasubramanian R, Jiménez MC, Li J, Guo X, Cruz DE, Gao Y, Huang T, Zeleznik OA, Ngo D, Liu S, Rosal MC, Nassir R, Paynter NP, Albert CM, Tracy RP, Durda P, Liu Y, Taylor KD, Johnson WC, Sun Q, Rimm EB, Eliassen AH, Rich SS, Rotter JI, Gerszten RE, Clish CB, Rexrode KM.

Circ Res. 2022 09 16. 131(7):601-615. PMID: 36052690