The Prostate Stromal Transcriptome in Aggressive and Lethal Prostate Cancer.
Ma C, Zhou Y, Fanelli GN, Stopsack KH, Fiorentino M, Zadra G, Mucci LA, Loda M, Tyekucheva S, Penney KL.
Mol Cancer Res. 2023 03 01. 21(3):253-260. PMID: 36511902
My major area of research and teaching is cancer epidemiology. I am the Director of the Cancer Epidemiology and Cancer Prevention Program (Area of Interest) within the Department of Epidemiology here at the Harvard T.H. Chan School of Public Health (HSPH). In addition, I am Leader of the Cancer Epidemiology Program at the Dana-Farber/Harvard Cancer Center.
After receiving my doctoral degree in epidemiology at the Harvard T.H. Chan School of Public Health (formerly the Harvard School of Public Health), I trained as a post-doctoral fellow in cancer epidemiology at the Karolinska Institutet, Sweden. At the Karolinska, I gained expertise in using nationwide health registries to examine cancer etiology and formed a long-term partnership with epidemiology colleagues in the Nordic countries. For the past 9 years, my primary faculty appointment has been at the Harvard Chan School, where my research uses integrative molecular epidemiology approaches within cohorts in the United States and globally to investigate research questions focused on cancer etiology, mortality, and survivorship. I serve as co-Principal Investigator for the Health Professionals Follow-up Study (https://sites.sph.harvard.edu/hpfs/) as well as IRONMAN (see below). Below is a summary of some major areas of interest.
Ma C, Zhou Y, Fanelli GN, Stopsack KH, Fiorentino M, Zadra G, Mucci LA, Loda M, Tyekucheva S, Penney KL.
Mol Cancer Res. 2023 03 01. 21(3):253-260. PMID: 36511902
Ma C, Ericsson C, Carlsson SV, Lilja H, Kibel A, Graff RE, Plym A, Giovannucci E, Mucci LA, Preston MA, Penney KL.
Eur Urol Open Sci. 2023 Apr. 50:27-30. PMID: 36861107
Watts EL, Perez-Cornago A, Fensom GK, Smith-Byrne K, Noor U, Andrews CD, Gunter MJ, Holmes MV, Martin RM, Tsilidis KK, Albanes D, Barricarte A, Bueno-de-Mesquita HB, Cohn BA, Deschasaux-Tanguy M, Dimou NL, Ferrucci L, Flicker L, Freedman ND, Giles GG, Giovannucci EL, Haiman CA, Hankey GJ, Holly JMP, Huang J, Huang WY, Hurwitz LM, Kaaks R, Kubo T, Le Marchand L, MacInnis RJ, Männistö S, Metter EJ, Mikami K, Mucci LA, Olsen AW, Ozasa K, Palli D, Penney KL, Platz EA, Pollak MN, Roobol MJ, Schaefer CA, Schenk JM, Stattin P, Tamakoshi A, Thysell E, Tsai CJ, Touvier M, Van Den Eeden SK, Weiderpass E, Weinstein SJ, Wilkens LR, Yeap BB, Allen NE, Key TJ, Travis RC.
Int J Epidemiol. 2023 02 08. 52(1):71-86. PMID: 35726641
Stopsack KH, Mucci LA, Tworoger SS, Kang JH, Eliassen AH, Willett WC, Stampfer MJ.
Epidemiology. 2023 Jan 31. PMID: 36719725
Wang A, Xu Y, Yu Y, Nead KT, Kim T, Xu K, Dadaev T, Saunders E, Sheng X, Wan P, Pooler L, Xia LY, Chanock S, Berndt SI, Gapstur SM, Stevens V, Albanes D, Weinstein SJ, Gnanapragasam V, Giles GG, Nguyen-Dumont T, Milne RL, Pomerantz MM, Schmidt JA, Stopsack KH, Mucci LA, Catalona WJ, Hetrick KN, Doheny KF, MacInnis RJ, Southey MC, Eeles RA, Wiklund F, Kote-Jarai Z, de Smith AJ, Conti DV, Huff C, Haiman CA, Darst BF.
Hum Mol Genet. 2023 01 13. 32(3):489-495. PMID: 36018819
Stopsack KH, Su XA, Vaselkiv JB, Graff RE, Ebot EM, Pettersson A, Lis RT, Fiorentino M, Loda M, Penney KL, Lotan TL, Mucci LA.
Mol Cancer Res. 2023 01 03. 21(1):14-23. PMID: 36125519
Ericsson CI, Pacheco LS, Romanos-Nanclares A, Ecsedy E, Giovannucci EL, Eliassen AH, Mucci LA, Fu BC.
Cancer Prev Res (Phila). 2022 Dec 09. PMID: 36490225
Zhang Y, Stopsack KH, Wu K, Song M, Mucci LA, Giovannucci E.
J Urol. 2023 03. 209(3):549-556. PMID: 36453265
Zhou CD, Pettersson A, Plym A, Tyekucheva S, Penney KL, Sesso HD, Kantoff PW, Mucci LA, Stopsack KH.
Cancer Prev Res (Phila). 2022 12 01. 15(12):815-825. PMID: 36125434
Plym A, Zhang Y, Stopsack KH, Jee YH, Wiklund F, Kibel AS, Kraft P, Giovannucci E, Penney KL, Mucci LA.
Clin Cancer Res. 2022 11 14. 28(22):4926-4933. PMID: 36103261
Frequent ejaculation has been linked with decreased prostate cancer risk. One reason may be that frequent ejaculation may help clear potentially cancer-causing substances from the prostate, according to Harvard Chan School's Lorelei Mucci.
Dietary patterns that are associated with inflammation and insulinemia—a condition marked by high levels of insulin in the blood—may put men at an increased risk for aggressive forms of prostate cancer, according to new research led by Harvard…
Among people with prostate cancer, higher levels of aneuploidy—a state in which a cell has too few or too many copies of some chromosomes—is associated with more aggressive and lethal forms of the cancer, according to new research…
Certain foods have been linked to prostate cancer risk—and a man’s risk of dying prematurely from the disease.
October 23, 2018 –Prostate cancer is among the most common forms of cancer affecting men today. In 2018, more than 1.2 million new cases will be diagnosed globally, according to the International Agency for Research on Cancer. While…