Plasma Biomarker Profiles for Premature and Nonpremature Coronary Heart Disease in Women.
Dugani SB, Moorthy MV, Demler OV, Li C, Ridker PM, Glynn RJ, Mora S.
Clin Chem. 2024 Mar 13. PMID: 38472127
As a biostatistician working at the Division of Preventive Medicine at Brigham and Women’s Hospital, my research interests are three-fold:
1) conducting biomarker discovery studies using high throughput metabolomics and other -omics data;
2) analysis of Electronic Health Records data;
3) methodological statistical research on building valid risk prediction models.
My clinical research focuses on the mechanistic pathways of cardiovascular disease development and progression.
The following publications highlight some of my research activities:
1. Kessler RC, Bauer M, Bishop T, Demler O, Dobscha S, Gildea S, Goulet J, Karras E, Kreyenbuhl J, Landes S, Liu H. Using administrative data to predict suicide after psychiatric hospitalization. Frontiers in Psychiatry. 2020;11:390.
2. Sels D, Dashti H, Mora S, Demler O, Demler E. Quantum approximate Bayesian computation for NMR model inference. arXiv preprint arXiv:1910.14221. 2019 Oct 31.
3. Antonelli J, Claggett BL, Henglin M, Kim A, Ovsak G, Kim N, Deng K, Rao K, Tyagi O, Watrous JD, Lagerborg KA, Hushcha PV, Demler OV, Mora S, Niiranen TJ, Pereira AC, Jain M, Cheng S. Statistical Workflow for Feature Selection in Human Metabolomics Data. Metabolites. 2019 Jul 12; 9(7). PMID: 31336989.
4. Demler OV, Pencina MJ, Cook NR, D'Agostino RB. Asymptotic distribution of AUC, NRIs, and IDI based on theory of U-statistics. Stat Med. 2017 Sep 20; 36(21):3334-3360. PMID: 28627112.
5. Demler OV, Paynter NP, Cook NR. Tests of calibration and goodness-of-fit in the survival setting. Stat Med. 2015 May 10; 34(10):1659-80. PMID: 25684707.
6. Demler OV, Pencina MJ, D'Agostino RB. Impact of correlation on predictive ability of biomarkers. Stat Med. 2013 Oct 30; 32(24):4196-210. PMID: 23640729.
Dugani SB, Moorthy MV, Demler OV, Li C, Ridker PM, Glynn RJ, Mora S.
Clin Chem. 2024 Mar 13. PMID: 38472127
Solomon DH, Demler O, Rist PM, Santacroce L, Tawakol A, Giles JT, Liao KP, Bathon JM.
J Am Heart Assoc. 2024 Mar 05. 13(5):e032095. PMID: 38416140
Hoshi RA, Plavša B, Liu Y, Trbojevic-Akmacic I, Glynn RJ, Ridker PM, Cummings RD, Gudelj I, Lauc G, Demler OV, Mora S.
Circ Res. 2024 03. 134(5):e3-e14. PMID: 38348651
Ahmad S, Moorthy MV, Lee IM, Ridker PM, Manson JE, Buring J, Demler OV, Mora S.
medRxiv. 2023 Oct 03. PMID: 37873228
McGrath JJ, Al-Hamzawi A, Alonso J, Altwaijri Y, Andrade LH, Bromet EJ, Bruffaerts R, de Almeida JMC, Chardoul S, Chiu WT, Degenhardt L, Demler OV, Ferry F, Gureje O, Haro JM, Karam EG, Karam G, Khaled SM, Kovess-Masfety V, Magno M, Medina-Mora ME, Moskalewicz J, Navarro-Mateu F, Nishi D, Plana-Ripoll O, Posada-Villa J, Rapsey C, Sampson NA, Stagnaro JC, Stein DJ, Ten Have M, Torres Y, Vladescu C, Woodruff PW, Zarkov Z, Kessler RC.
Lancet Psychiatry. 2023 09. 10(9):668-681. PMID: 37531964
Kessler RC, Bauer MS, Bishop TM, Bossarte RM, Castro VM, Demler OV, Gildea SM, Goulet JL, King AJ, Kennedy CJ, Landes SJ, Liu H, Luedtke A, Mair P, Marx BP, Nock MK, Petukhova MV, Pigeon WR, Sampson NA, Smoller JW, Miller A, Haas G, Benware J, Bradley J, Owen RR, House S, Urosevic S, Weinstock LM.
JAMA Psychiatry. 2023 03 01. 80(3):230-240. PMID: 36652267
Birukov A, Plavša B, Eichelmann F, Kuxhaus O, Hoshi RA, Rudman N, Štambuk T, Trbojevic-Akmacic I, Schiborn C, Morze J, Mihelcic M, Cindric A, Liu Y, Demler O, Perola M, Mora S, Schulze MB, Lauc G, Wittenbecher C.
Diabetes Care. 2022 11 01. 45(11):2729-2736. PMID: 36174116
Hoshi RA, Liu Y, Luttmann-Gibson H, Tiwari S, Giulianini F, Andres AM, Watrous JD, Cook NR, Costenbader KH, Okereke OI, Ridker PM, Manson JE, Lee IM, Vinayagamoorthy M, Cheng S, Copeland T, Jain M, Chasman DI, Demler OV, Mora S.
Circ Res. 2022 08 05. 131(4):e84-e99. PMID: 35862024
Henglin M, Claggett BL, Antonelli J, Alotaibi M, Magalang GA, Watrous JD, Lagerborg KA, Ovsak G, Musso G, Demler OV, Vasan RS, Larson MG, Jain M, Cheng S.
Metabolites. 2022 Jun 04. 12(6). PMID: 35736452
Dugani SB, Moorthy MV, Li C, Demler OV, Alsheikh-Ali AA, Ridker PM, Glynn RJ, Mora S.
JAMA Cardiol. 2021 04 01. 6(4):437-447. PMID: 33471027