Patrick Musicha

Genomic insights into the 2022-2023Vibrio cholerae outbreak in Malawi.

Chaguza C, Chibwe I, Chaima D, Musicha P, Ndeketa L, Kasambara W, Mhango C, Mseka UL, Bitilinyu-Bangoh J, Mvula B, Kipandula W, Bonongwe P, Munthali RJ, Ngwira S, Mwendera CA, Kalizang'oma A, Jambo KC, Kambalame D, Kamng'ona AW, Steele AD, Chauma-Mwale A, Hungerford D, Kagoli M, Nyaga MM, Dube Q, French N, Msefula CL, Cunliffe NA, Jere KC.

Nat Commun. 2024 Jul 26. 15(1):6291. PMID: 39060226

Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerations.

Heinz E, Pearse O, Zuza A, Bilima S, Msefula C, Musicha P, Siyabu P, Tewesa E, Graf FE, Lester R, Lissauer S, Cornick J, Lewis JM, Kawaza K, Thomson NR, Feasey NA.

Genome Med. 2024 05 06. 16(1):67. PMID: 38711148

Prevalence, risk factors, and antimicrobial resistance of endemic healthcare-associated infections in Africa: a systematic review and meta-analysis.

Bunduki GK, Masoamphambe E, Fox T, Musaya J, Musicha P, Feasey N.

BMC Infect Dis. 2024 Feb 02. 24(1):158. PMID: 38302895

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs).

Cocker D, Sammarro M, Chidziwisano K, Elviss N, Jacob ST, Kajumbula H, Mugisha L, Musoke D, Musicha P, Roberts AP, Rowlingson B, Singer AC, Byrne RL, Edwards T, Lester R, Wilson CN, Hollihead B, Thomson NR, Jewell CP, Morse T, Feasey NA.

Wellcome Open Res. 2022. 7:55. PMID: 38817338

Evidence of widespread endemic populations of highly multidrug resistant Klebsiella pneumoniae in hospital settings in Hanoi, Vietnam: a prospective cohort study.

Pham MH, Hoi LT, Beale MA, Khokhar FA, Hoa NT, Musicha P, Blackwell GA, Long HB, Huong DT, Binh NG, Co DX, Giang T, Bui C, Tran HN, Bryan J, Herrick A, Feltwell T, Nadjm B, Parkhill J, van Doorn HR, Trung NV, Van Kinh N, Török ME, Thomson NR.

Lancet Microbe. 2023 04. 4(4):e255-e263. PMID: 36801013

Genomic epidemiology on the move.

Wilson CN, Musicha P, Beale MA.

Nat Rev Microbiol. 2023 02. 21(2):69. PMID: 36536144

Effect of resistance to third-generation cephalosporins on morbidity and mortality from bloodstream infections in Blantyre, Malawi: a prospective cohort study.

Lester R, Musicha P, Kawaza K, Langton J, Mango J, Mangochi H, Bakali W, Pearse O, Mallewa J, Denis B, Bilima S, Gordon SB, Lalloo DG, Jewell CP, Feasey NA.

Lancet Microbe. 2022 12. 3(12):e922-e930. PMID: 36335953

Genomic investigation of a suspected Klebsiella pneumoniae outbreak in a neonatal care unit in sub-Saharan Africa.

Cornick J, Musicha P, Peno C, Seager E, Iroh Tam PY, Bilima S, Bennett A, Kennedy N, Feasey N, Heinz E, Cain AK.

Microb Genom. 2021 11. 7(11). PMID: 34793293

A novel air-dried multiplex high-resolution melt assay for the detection of extended-spectrum ß-lactamase and carbapenemase genes.

Cubas-Atienzar AI, Williams CT, Karkey A, Dongol S, Sulochana M, Rajendra S, Hobbs G, Evans K, Musicha P, Feasey N, Cuevas LE, Adams ER, Edwards T.

J Glob Antimicrob Resist. 2021 12. 27:123-131. PMID: 34482019

Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients.

León-Sampedro R, DelaFuente J, Díaz-Agero C, Crellen T, Musicha P, Rodríguez-Beltrán J, de la Vega C, Hernández-García M, López-Fresneña N, Ruiz-Garbajosa P, Cantón R, Cooper BS, San Millán Á.

Nat Microbiol. 2021 05. 6(5):606-616. PMID: 33782584