Rest-activity rhythms across the lifespan: cross-sectional findings from the US representative National Health and Nutrition Examination Survey.
Wallace DA, Johnson DA, Redline S, Sofer T, Kossowsky J.
Sleep. 2023 Nov 08. 46(11). PMID: 37610882
I direct the Program in Sleep Medicine Epidemiology at BWH. Our goals are to conduct rigorous and population-based research to: elucidate the role of genetics, early life developmental factors, and environmental exposures on sleep health; identify how social and environmental factors shape sleep health disparities which in turn drive chronic health disparities; and identify the role of sleep interventions in improving health, including cardiovascular, metabolic, and cognitive disorders.
Within the Program, we support the following Resources:
The BWH Sleep Reading Center (www.bostonsleep.org), an international core laboratory that provides leadership in the design and implementation of sleep data collection for numerous clinical trials and cohort studies. It spearheaded efforts at establishing rigorous quality control procedures for multi-site sleep research and for integrating advanced signal processing analytics into large scale-epidemiological datasets to provide quantitative biomarkers of sleep and sleep disorders.
The National Sleep Research Resource (NSRR; www.sleepdata.org), a NHLBI-data and tool repository and community engagement resource that shares large quantities of polysomnography, actigraphy and other data coupled with tools to structure, harmonize, visualize and analyze sleep data.
The Sleep Apnea Patient-Centered Outcomes Network (MyApnea; www.myapnea.org), a web-based portal to promote sleep apnea patient support and patient engagement in research.
I am the recipient of a NHLBI Outstanding Investigator Award (R35) that supports a research and training program, Phenotypic and Genomic Signatures For Sleep Apnea. This program brings together trainees and experts in epidemiology, genetic and sleep/respiratory physiology to identify biomarkers and molecular mechanisms for sleep apnea risk, models interactions between sleep disorders and genetic risk factors (G*E), and attempts to resolve the heterogeneity in sleep apnea that predicts differences in outcomes and treatment response.
I co-direct the following multi-center clinical trials:
Pediatric Adenotonsillectomy Trial (PATS; patstrial.org)
Impact of Low Flow Oxygen on Hospital Admissions and Mortality in Heart Failure and Central Sleep Apnea (LOFT-HF; lofthf.study).
I co-lead a cohort study examining the impact of the home environment on sleep disorders among children in low income urban neighborhoods. (Environmental Assessment of Sleep in Youth).
BA, 05/1979, Six Year Medical Honors Program
Boston University, Boston
MD, 05/1979, Medicine
Boston University School of Medicine, Boston
MPH, 05/1986, Respiratory Epidemiology
Harvard School Of Public Health, Boston
William C Dement Scientific Achievement Award
American Academy of Sleep Medicine
Scientific Recognition Award
American Thoracic Society
Association of American Physicians
Sleep In Infancy and Childhood Award
Annenberg
Spotlight on Women's Scholarship
Case Western Reserve University
Wallace DA, Johnson DA, Redline S, Sofer T, Kossowsky J.
Sleep. 2023 Nov 08. 46(11). PMID: 37610882
Esmaeili N, Labarca G, Hu WH, Vena D, Messineo L, Gell L, Hajipour M, Taranto-Montemurro L, Sands SA, Redline S, Wellman A, Sehhati M, Azarbarzin A.
Ann Am Thorac Soc. 2023 11. 20(11):1633-1641. PMID: 37531573
Nance RM, Fohner AE, McClelland RL, Redline S, Bryan RN, Fitzpatrick A, Habes M, Longstreth WT, Schwab RJ, Wiemken AS, Heckbert SR.
BMC Neurol. 2023 Oct 31. 23(1):394. PMID: 37907860
Jakubek YA, Zhou Y, Stilp A, Bacon J, Wong JW, Ozcan Z, Arnett D, Barnes K, Bis JC, Boerwinkle E, Brody JA, Carson AP, Chasman DI, Chen J, Cho M, Conomos MP, Cox N, Doyle MF, Fornage M, Guo X, Kardia SLR, Lewis JP, Loos RJF, Ma X, Machiela MJ, Mack TM, Mathias RA, Mitchell BD, Mychaleckyj JC, North K, Pankratz N, Peyser PA, Preuss MH, Psaty B, Raffield LM, Vasan RS, Redline S, Rich SS, Rotter JI, Silverman EK, Smith JA, Smith AP, Taub M, Taylor KD, Yun J, Li Y, Desai P, Bick AG, Reiner AP, Scheet P, Auer PL.
Nat Genet. 2023 Nov. 55(11):1912-1919. PMID: 37904051
Himali JJ, Baril AA, Cavuoto MG, Yiallourou S, Wiedner CD, Himali D, DeCarli C, Redline S, Beiser AS, Seshadri S, Pase MP.
JAMA Neurol. 2023 Oct 30. PMID: 37902739
Huang T, Goodman M, Wang H, Sofer T, Tworoger SS, Stampfer MJ, Saxena R, Redline S.
Am J Respir Crit Care Med. 2023 Oct 26. PMID: 37883203
Pershad Y, Mack T, Poisner H, Jakubek YA, Stilp AM, Mitchell BD, Lewis JP, Boerwinkle E, Loos RJ, Chami N, Wang Z, Barnes K, Pankratz N, Fornage M, Redline S, Psaty BM, Bis JC, Shojaie A, Silverman EK, Cho MH, Yun J, DeMeo D, Levy D, Johnson A, Mathias R, Taub M, Arnett D, North K, Raffield LM, Carson A, Doyle MF, Rich SS, Rotter JI, Guo X, Cox N, Roden DM, Franceschini N, Desai P, Reiner A, Auer PL, Scheet P, Jaiswal S, Weinstock JS, Bick AG.
medRxiv. 2023 Oct 21. PMID: 37905118
Wallace DA, Qiu X, Schwartz J, Huang T, Scheer FAJL, Redline S, Sofer T.
medRxiv. 2023 Oct 12. PMID: 37873226
Steier JS, Bogan RK, Cano-Pumarega IM, Fleetham JA, Insalaco G, Lal C, Pépin JL, Randerath WJ, Redline S, Malhotra A.
Sleep Med. 2023 Oct 09. 112:104-115. PMID: 37839271
Wang Y, Selvaraj MS, Li X, Li Z, Holdcraft JA, Arnett DK, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Cade BE, Carlson JC, Carson AP, Chen YI, Curran JE, de Vries PS, Dutcher SK, Ellinor PT, Floyd JS, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, Guo X, He J, Heard-Costa N, Hildalgo B, Hou L, Irvin MR, Joehanes R, Kaplan RC, Kardia SL, Kelly TN, Kim R, Kooperberg C, Kral BG, Levy D, Li C, Liu C, Lloyd-Jone D, Loos RJ, Mahaney MC, Martin LW, Mathias RA, Minster RL, Mitchell BD, Montasser ME, Morrison AC, Murabito JM, Naseri T, O'Connell JR, Palmer ND, Preuss MH, Psaty BM, Raffield LM, Rao DC, Redline S, Reiner AP, Rich SS, Ruepena MS, Sheu WH, Smith JA, Smith A, Tiwari HK, Tsai MY, Viaud-Martinez KA, Wang Z, Yanek LR, Zhao W, Rotter JI, Lin X, Natarajan P, Peloso GM.
Am J Hum Genet. 2023 Oct 05. 110(10):1704-1717. PMID: 37802043
Insomnia, sleep apnea, snoring, and other sleep difficulties common among older adults are more common among blacks, Chinese, and Hispanics in America than in whites and may contribute to health disparities, according to a study led by Harvard…
Harvard Catalyst fosters relationships across the University June 26, 2014 — Fathers tend not to be included in research on how kids are fed at home, despite increasing evidence that men are contributing more time to the daily…