I direct the Program in Sleep Medicine Epidemiology at BWH. Our goals are to conduct rigorous and population-based research to: elucidate the role of genetics, early life developmental factors, and environmental exposures on sleep health; identify how social and environmental factors shape sleep health disparities which in turn drive chronic health disparities; and identify the role of sleep interventions in improving health, including cardiovascular, metabolic, and cognitive disorders.
Within the Program, we support the following Resources:
The BWH Sleep Reading Center (www.bostonsleep.org), an international core laboratory that provides leadership in the design and implementation of sleep data collection for numerous clinical trials and cohort studies. It spearheaded efforts at establishing rigorous quality control procedures for multi-site sleep research and for integrating advanced signal processing analytics into large scale-epidemiological datasets to provide quantitative biomarkers of sleep and sleep disorders.
The National Sleep Research Resource (NSRR; www.sleepdata.org), a NHLBI-data and tool repository and community engagement resource that shares large quantities of polysomnography, actigraphy and other data coupled with tools to structure, harmonize, visualize and analyze sleep data.
The Sleep Apnea Patient-Centered Outcomes Network (MyApnea; www.myapnea.org), a web-based portal to promote sleep apnea patient support and patient engagement in research.
I am the recipient of a NHLBI Outstanding Investigator Award (R35) that supports a research and training program, Phenotypic and Genomic Signatures For Sleep Apnea. This program brings together trainees and experts in epidemiology, genetic and sleep/respiratory physiology to identify biomarkers and molecular mechanisms for sleep apnea risk, models interactions between sleep disorders and genetic risk factors (G*E), and attempts to resolve the heterogeneity in sleep apnea that predicts differences in outcomes and treatment response.
I co-direct the following multi-center clinical trials:
Pediatric Adenotonsillectomy Trial (PATS; patstrial.org)
Impact of Low Flow Oxygen on Hospital Admissions and Mortality in Heart Failure and Central Sleep Apnea (LOFT-HF; lofthf.study).
I co-lead a cohort study examining the impact of the home environment on sleep disorders among children in low income urban neighborhoods. (Environmental Assessment of Sleep in Youth).
BA, 05/1979, Six Year Medical Honors Program
Boston University, Boston
MD, 05/1979, Medicine
Boston University School of Medicine, Boston
MPH, 05/1986, Respiratory Epidemiology
Harvard School Of Public Health, Boston
William C Dement Scientific Achievement Award
American Academy of Sleep Medicine
Scientific Recognition Award
American Thoracic Society
Association of American Physicians
Sleep In Infancy and Childhood Award
Annenberg
Spotlight on Women's Scholarship
Case Western Reserve University
Wallace ML, Redline S, Oryshkewych N, Hoepel SJW, Luik AI, Stone KL, Kolko RP, Chung J, Leng Y, Robbins R, Zhang Y, Barnes LL, Lim AS, Yu L, Buysse DJ.
Sleep. 2024 Sep 09. 47(9). PMID: 38752786
Huffman JE, Nicholas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, Emmert DB, Ghanbari M, Haessler J, Hottenga JJ, Kleber ME, Le NQ, Lee J, Lewis JP, Li-Gao R, Luan J, Malmberg AL, Mangino M, Marioni R, Martinez-Perez A, Pankratz N, Polasek O, Richmond A, Rodriguez BAT, Rotter JI, Steri M, Suchon P, Trompet S, Weiss S, Zare M, Auer PL, Cho M, Christofidou P, Davies G, de Geus EJ, Deleuze JF, Delgado GE, Ekunwe L, Faraday N, Gogele M, Greinacher A, Gao H, Howard TE, Joshi PK, Kilpeläinen TO, Lahti J, Linneberg A, Naitza S, Noordam R, Vergés FP, Rich SS, Rosendaal FR, Rudan I, Ryan KA, Souto JCC, van Rooij FJA, Wang H, Zhao W, Becker L, Beswick A, Brown MR, Cade B, Campbell H, Cho K, Crapo J, Curran J, de Maat MPM, Doyle MF, Elliott P, Floyd JS, Fuchsberger C, Grarup N, Guo X, Harris S, Hou L, Kolcic I, Kooperberg C, Menni C, Nauck M, O'Connell JR, Orru V, Psaty BM, Räikkönen K, Smith JA, Soria JM, Stott D, van Hylckama Vlieg A, Watkins H, Willemsen G, Wilson PW, Ben-Shlomo Y, Blangero J, Boomsma D, Cox SR, Dehghan A, Eriksson JG, Fiorillo E, Fornage M, Hansen T, Hayward C, Ikram MA, Jukema JW, Kardia S, Lange L, Maerz W, Mathias R, Mitchell BD, Mook-Kanamori DO, Morange PE, Pedersen O, Pramstaller PP, Redline S, Reiner AP, Ridker PM, Silverman EK, Spector TD, Volker U, Wareham N, Wilson J, Yao J, Tregouet DA, Johnson AD, Wolberg AS, de Vries PS, Sabater-Lleal M, Morrison A, Smith NL.
Blood. 2024 Sep 03. PMID: 39226462
Kianersi S, Wang H, Sofer T, Noordam R, Phillips A, Rutter MK, Redline S, Huang T.
Diabetes Care. 2024 Sep 01. 47(9):1647-1655. PMID: 39017683
Kirkham EM, Ishman S, Baldassari CM, Mitchell RB, Naqvi SK, Tapia IE, Elden LM, Hassan F, Ibrahim S, Ross K, Cen M, Wang R, Redline S, Chervin RD.
JAMA Otolaryngol Head Neck Surg. 2024 Aug 22. PMID: 39172463
Wang J, Gueye-Ndiaye S, Castro-Diehl C, Bhaskar S, Li L, Tully M, Rueschman M, Owens J, Gold DR, Chen J, Phipatanakul W, Adamkiewicz G, Redline S.
Sleep Health. 2024 Aug 01. PMID: 39095254
Mann DL, Staykov E, Georgeson T, Azarbarzin A, Kainulainen S, Redline S, Sands SA, Terrill PI.
Ann Am Thorac Soc. 2024 Aug. 21(8):1186-1193. PMID: 38530665
Stankeviciute L, Chhatwal JP, Levin R, Pinilla V, Schultz AP, Redline S, Johnson KA, Sperling RA, Kozhemiako N, Purcell S, Djonlagic I.
Alzheimers Dement (Amst). 2024 Jul-Sep. 16(3):e12616. PMID: 39077684
Huang T, Kianersi S, Wang H, Potts KS, Noordam R, Sofer T, Rutter MK, Redline S.
medRxiv. 2024 Jul 27. PMID: 39108534
Alex RM, Mann DL, Azarbarzin A, Vena D, Gell LK, Wellman A, Grobman WA, Facco FL, Silver RM, Pien GW, Louis JM, Zee PC, Rueschman M, Sofer T, Redline S, Sands SA.
Eur Respir J. 2024 Jul. 64(1). PMID: 38575160
Wang H, Nagarajan P, Winkler T, Bentley A, Miller C, Kraja A, Schwander K, Lee S, Wang W, Brown M, Morrison J, Giri A, O'Connell J, Bartz T, de Las Fuentes L, Gudmundsdottir V, Guo X, Harris S, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer N, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most P, Wang Y, Weiss S, Westerman K, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja A, Arzt M, Aschard H, Attia J, Bazzano L, Breyer M, Brody J, Cade B, Chen HH, Chen YI, Chen Z, de Vries P, Dimitrov L, Do A, Du J, Dupont C, Edwards T, Evans M, Faquih T, Felix S, Fisher-Hoch S, Floyd J, Graff M, Charles Gu C, Gu D, Hairston K, Hanley A, Heid I, Heikkinen S, Highland H, Hood M, Kähönen M, Karvonen-Gutierrez C, Kawaguchi T, Kazuya S, Tanika K, Komulainen P, Levy D, Lin H, Liu P, Marques-Vidal P, McCormick J, Mei H, Meigs J, Menni C, Nam K, Nolte I, Pacheco N, Petty L, Polikowsky H, Province M, Psaty B, Raffield L, Raitakari O, Rich S, Riha R, Risch L, Risch M, Ruiz-Narvaez E, Scott R, Sitlani C, Smith J, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, van Dijk KW, Wilson O, Xia R, Yao J, Young K, Zhang R, Zhu X, Below J, Böger C, Conen D, Cox S, Dörr M, Feitosa M, Fox E, Franceschini N, Gharib S, Gudnason V, Harlow S, He J, Holliday E, Kutalik Z, Lakka T, Lawlor D, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison A, Penninx BWJH, Peyser P, Rotter J, Snieder H, Spector T, Wagenknecht L, Wareham N, Zonderman A, North K, Fornage M, Hung A, Manning A, Gauderman W, Chen H, Munroe P, Rao D, van Heemst D, Redline S, Noordam R.
Res Sq. 2024 Jul 17. PMID: 39070651
Insomnia, sleep apnea, snoring, and other sleep difficulties common among older adults are more common among blacks, Chinese, and Hispanics in America than in whites and may contribute to health disparities, according to a study led by Harvard…
Harvard Catalyst fosters relationships across the University June 26, 2014 — Fathers tend not to be included in research on how kids are fed at home, despite increasing evidence that men are contributing more time to the daily…
