Tomotaka Ugai

Revisiting social MPE: an integration of molecular pathological epidemiology and social science in the new era of precision medicine.

Dai J, Nishi A, Tran N, Yamamoto Y, Dewey G, Ugai T, Ogino S.

Expert Rev Mol Diagn. 2021 Jul 26. 1-18. PMID: 34253130

Smoking and Incidence of Colorectal Cancer Subclassified by Tumor-Associated Macrophage Infiltrates.

Ugai T, Väyrynen JP, Haruki K, Akimoto N, Lau MC, Zhong R, Kishikawa J, Väyrynen SA, Zhao M, Fujiyoshi K, Costa AD, Borowsky J, Arima K, Guerriero JL, Fuchs CS, Zhang X, Song M, Wang M, Giannakis M, Meyerhardt JA, Nowak JA, Ogino S.

J Natl Cancer Inst. 2021 Jul 15. PMID: 34264325

Discovery and features of an alkylating signature in colorectal cancer.

Gurjao C, Zhong R, Haruki K, Li YY, Spurr LF, Lee-Six H, Reardon B, Ugai T, Zhang X, Cherniack AD, Song M, Van Allen EM, Meyerhardt JA, Nowak JA, Giovannucci EL, Fuchs CS, Wu K, Ogino S, Giannakis M.

Cancer Discov. 2021 Jun 17. PMID: 34140290

Tumor Long Interspersed Nucleotide Element-1 (LINE-1) Hypomethylation in Relation to Age of Colorectal Cancer Diagnosis and Prognosis.

Akimoto N, Zhao M, Ugai T, Zhong R, Lau MC, Fujiyoshi K, Kishikawa J, Haruki K, Arima K, Twombly TS, Zhang X, Giovannucci EL, Wu K, Song M, Chan AT, Cao Y, Meyerhardt JA, Ng K, Giannakis M, Väyrynen JP, Nowak JA, Ogino S.

Cancers (Basel). 2021 Apr 22. 13(9). PMID: 33922024

Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment.

Väyrynen JP, Haruki K, Väyrynen SA, Lau MC, Dias Costa A, Borowsky J, Zhao M, Ugai T, Kishikawa J, Akimoto N, Zhong R, Shi S, Chang TW, Fujiyoshi K, Arima K, Twombly TS, Da Silva A, Song M, Wu K, Zhang X, Chan AT, Nishihara R, Fuchs CS, Meyerhardt JA, Giannakis M, Ogino S, Nowak JA.

J Immunother Cancer. 2021 Apr. 9(4). PMID: 33931472

Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment.

Borowsky J, Haruki K, Lau MC, Dias Costa A, Väyrynen JP, Ugai T, Arima K, da Silva A, Felt KD, Zhao M, Gurjao C, Twombly TS, Fujiyoshi K, Väyrynen SA, Hamada T, Mima K, Bullman S, Harrison TA, Phipps AI, Peters U, Ng K, Meyerhardt JA, Song M, Giovannucci EL, Wu K, Zhang X, Freeman GJ, Huttenhower C, Garrett WS, Chan AT, Leggett BA, Whitehall VLJ, Walker N, Brown I, Bettington M, Nishihara R, Fuchs CS, Lennerz JK, Giannakis M, Nowak JA, Ogino S.

Clin Cancer Res. 2021 May 15. 27(10):2816-2826. PMID: 33632927

Rising incidence of early-onset colorectal cancer - a call to action.

Akimoto N, Ugai T, Zhong R, Hamada T, Fujiyoshi K, Giannakis M, Wu K, Cao Y, Ng K, Ogino S.

Nat Rev Clin Oncol. 2021 04. 18(4):230-243. PMID: 33219329

A Modified Tumor-Node-Metastasis Classification for Primary Operable Colorectal Cancer.

Zhang C, Mei Z, Pei J, Abe M, Zeng X, Huang Q, Nishiyama K, Akimoto N, Haruki K, Nan H, Meyerhardt JA, Zhang R, Li X, Ogino S, Ugai T.

JNCI Cancer Spectr. 2021 Feb. 5(1):pkaa093. PMID: 33554032

Risk Factors and Incidence of Colorectal Cancer According to Major Molecular Subtypes.

Wang L, He X, Ugai T, Haruki K, Lo CH, Hang D, Akimoto N, Fujiyoshi K, Wang M, Fuchs CS, Meyerhardt JA, Zhang X, Wu K, Chan AT, Giovannucci EL, Ogino S, Song M.

JNCI Cancer Spectr. 2021 Feb. 5(1):pkaa089. PMID: 33442661

The Prognostic Role of Macrophage Polarization in the Colorectal Cancer Microenvironment.

Väyrynen JP, Haruki K, Lau MC, Väyrynen SA, Zhong R, Dias Costa A, Borowsky J, Zhao M, Fujiyoshi K, Arima K, Twombly TS, Kishikawa J, Gu S, Aminmozaffari S, Shi S, Baba Y, Akimoto N, Ugai T, Da Silva A, Guerriero JL, Song M, Wu K, Chan AT, Nishihara R, Fuchs CS, Meyerhardt JA, Giannakis M, Ogino S, Nowak JA.

Cancer Immunol Res. 2021 01. 9(1):8-19. PMID: 33023967