Adjunct Faculty

Vincent Jaddoe

Adjunct Professor of Epidemiology

Epidemiology

vjaddoe@hsph.harvard.edu


Overview

Dr. Jaddoe (1974) is Pediatrician and Professor of Pediatric Epidemiology. He is Principal Investigator of the Generation R Study, a population-based prospective cohort study among 10,000 pregnant women and their children in Rotterdam, The Netherlands (www.generationr.nl). His research is focused on 3 main themes: (1) Maternal and fetal health;(2) Fetal and infant programming of common childhood diseases; (3) Genetics and epigenetics of common childhood diseases. General aim of this research is to explore how genetic variants and environmental exposures lead to maternal gestational complications, fetal and childhood developmental adaptation mechanisms, and risk factors for common diseases. Specific interest is in the identification of early critical periods and mechanisms leading to risk factors for diseases in later life. Main diseases of interest include cardiovascular disease, type 2 diabetes, obesity and respiratory diseases. Genetic association studies are embedded in the Early Growth Genetics (EGG) Consortium and Early Growth & Longitudinal Epidemiology (EAGLE) Consortium, in which various birth cohorts (>30,000 subjects) combine their genome wide association studies efforts.


Bibliography

Long-term cardiometabolic health in people born after assisted reproductive technology: a multi-cohort analysis.

Elhakeem A, Taylor AE, Inskip HM, Huang JY, Mansell T, Rodrigues C, Asta F, Blaauwendraad SM, Håberg SE, Halliday J, Harskamp-van Ginkel MW, He JR, Jaddoe VWV, Lewis S, Maher GM, Manios Y, McCarthy FP, Reiss IKM, Rusconi F, Salika T, Tafflet M, Qiu X, Åsvold BO, Burgner D, Chan JKY, Gagliardi L, Gaillard R, Heude B, Magnus MC, Moschonis G, Murray D, Nelson SM, Porta D, Saffery R, Barros H, Eriksson JG, Vrijkotte TGM, Lawlor DA.

Eur Heart J. 2023 Feb 06. PMID: 36740401

Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies.

Vinther JL, Cadman T, Avraam D, Ekstrøm CT, I A Sørensen T, Elhakeem A, Santos AC, Pinot de Moira A, Heude B, Iñiguez C, Pizzi C, Simons E, Voerman E, Corpeleijn E, Zariouh F, Santorelli G, Inskip HM, Barros H, Carson J, Harris JR, Nader JL, Ronkainen J, Strandberg-Larsen K, Santa-Marina L, Calas L, Cederkvist L, Popovic M, Charles MA, Welten M, Vrijheid M, Azad M, Subbarao P, Burton P, Mandhane PJ, Huang RC, Wilson RC, Haakma S, Fernández-Barrés S, Turvey S, Santos S, Tough SC, Sebert S, Moraes TJ, Salika T, Jaddoe VWV, Lawlor DA, Nybo Andersen AM.

PLoS Med. 2023 01. 20(1):e1004036. PMID: 36701266