Negative frequency-dependent selection and asymmetrical transformation stabilise multi-strain bacterial population structures.
Harrow GL, Lees JA, Hanage WP, Lipsitch M, Corander J, Colijn C, Croucher NJ.
ISME J. 2021 Jan 06. PMID: 33408365
I am an Associate Professor of Epidemiology in the department of Epidemiology, and a faculty member in the Center for Communicable Disease Dynamics. I employ a mix of theoretical and laboratory work to research the evolution and epidemiology of infectious disease. After my PhD, I did post doctoral study at the University of Oxford and Imperial College London, before being awarded a Royal Society University Research Fellowship. Prior to joining the Center for Communicable Disease Dynamics, I was a Reader in the department of Infectious Disease Epidemiology at Imperial College London. There I worked extensively developing multilocus sequence typing (MLST; www.mlst.net) and analysis (MLSA) for the study of bacterial pathogens and species, as well as means of analyzing data developed using this method. I am particularly interested in using an evolutionary framework such as methods derived from population genetics to inform epidemiology. In 2012 I received the Fleming Prize for research in Microbiology and was the recipient of a 2012 ICAAC Young Investigator Award from the American Society for Microbiology.
Harrow GL, Lees JA, Hanage WP, Lipsitch M, Corander J, Colijn C, Croucher NJ.
ISME J. 2021 Jan 06. PMID: 33408365
Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BL.
Science. 2020 Dec 10. PMID: 33303686
Levin AT, Hanage WP, Owusu-Boaitey N, Cochran KB, Walsh SP, Meyerowitz-Katz G.
Eur J Epidemiol. 2020 Dec. 35(12):1123-1138. PMID: 33289900
Goldenfeld M, Nir-Paz R, Segal G, Bar-On E, Mendelson E, Mandelboim M, Wolf DG, Marom EM, Israely T, Achdout H, Rahav G, Hanage WP, Regev-Yochay G.
Prehosp Disaster Med. 2020 Nov 17. 1-4. PMID: 33198831
Choi B, Choudhary MC, Regan J, Sparks JA, Padera RF, Qiu X, Solomon IH, Kuo HH, Boucau J, Bowman K, Adhikari UD, Winkler ML, Mueller AA, Hsu TY, Desjardins M, Baden LR, Chan BT, Walker BD, Lichterfeld M, Brigl M, Kwon DS, Kanjilal S, Richardson ET, Jonsson AH, Alter G, Barczak AK, Hanage WP, Yu XG, Gaiha GD, Seaman MS, Cernadas M, Li JZ.
N Engl J Med. 2020 12 03. 383(23):2291-2293. PMID: 33176080
Hanage WP, Testa C, Chen JT, Davis L, Pechter E, Seminario P, Santillana M, Krieger N.
Eur J Epidemiol. 2020 Nov. 35(11):995-1006. PMID: 33136249
Krieger N, Testa C, Hanage WP, Chen JT.
Lancet. 2020 11 07. 396(10261):e81. PMID: 33169681
Azarian T, Martinez PP, Arnold BJ, Qiu X, Grant LR, Corander J, Fraser C, Croucher NJ, Hammitt LL, Reid R, Santosham M, Weatherholtz RC, Bentley SD, O'Brien KL, Lipsitch M, Hanage WP.
PLoS Biol. 2020 10. 18(10):e3000878. PMID: 33091022
Alwan NA, Burgess RA, Ashworth S, Beale R, Bhadelia N, Bogaert D, Dowd J, Eckerle I, Goldman LR, Greenhalgh T, Gurdasani D, Hamdy A, Hanage WP, Hodcroft EB, Hyde Z, Kellam P, Kelly-Irving M, Krammer F, Lipsitch M, McNally A, McKee M, Nouri A, Pimenta D, Priesemann V, Rutter H, Silver J, Sridhar D, Swanton C, Walensky RP, Yamey G, Ziauddeen H.
Lancet. 2020 10 31. 396(10260):e71-e72. PMID: 33069277
Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda J, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, Maclnnis BL.
medRxiv. 2020 Aug 25. PMID: 32869040
Experts agree that it’s not “if” there will be another pandemic, but “when”—and that we should learn from our mistakes during the current one if we want to fare better next time.
William Hanage, associate professor of epidemiology at Harvard Chan School, discusses two newly discovered coronavirus variants.
You’re listening to a press conference from the Harvard School of Public Health with Barry Bloom, professor of immunology and infectious diseases and former dean of the school, and William Hanage, associate professor of epidemiology and a faculty…
You're listening to a press conference from the Harvard School of Public Health with Barry Bloom, professor of immunology and infectious diseases and former dean of the school, and William Hanage, associate professor of epidemiology and a faculty…
An article co-authored by Harvard Chan School researchers assessed federal missteps in responding to the COVID-19 pandemic that have led the U.S. to experience some of the most severe outcomes in the world.