Mental disorders are a major, often overlooked challenge to population health both in the United States and globally.
Notably, one in five persons suffer from a mental disorder at some point in their lives. Major depression is projected to be the leading cause of burden of disease globally by 2030. Schizophrenic and bipolar disorders are in the top 10 leading causes of disability in low- and middle-income countries, while substance use disorders are in the top 10 list in high-income countries. Increasingly, mental disorders have been linked to higher risk of the development of and mortality from chronic diseases, such as type 2 diabetes and cardiovascular disease, as well as infectious diseases such as HIV.