Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to hexavalent chromium [Cr (VI)].
Lou J, Yu S, Feng L, Guo X, Wang M, Branco AT, Li T, Lemos B.
Environ Int. 2021 Mar 25. 153:106525. PMID: 33774497
Associate Professor
Bernardo Lemos
Bibliography
Characterization of hospital airborne SARS-CoV-2.
Stern RA, Koutrakis P, Martins MAG, Lemos B, Dowd SE, Sunderland EM, Garshick E.
Respir Res. 2021 Feb 26. 22(1):73. PMID: 33637076
Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors.
Tao T, Shi H, Wang M, Perez-Atayde AR, London WB, Gutierrez A, Lemos B, Durbin AD, Look AT.
J Exp Med. 2020 10 05. 217(10). PMID: 32728700
Cellular Imprinting Proteomics Assay: A Novel Method for Detection of Neural and Ocular Disorders Applied to Congenital Zika Virus Syndrome.
Rosa-Fernandes L, Barbosa RH, Dos Santos MLB, Angeli CB, Silva TP, Melo RCN, de Oliveira GS, Lemos B, Van Eyk JE, Larsen MR, Cardoso CA, Palmisano G.
J Proteome Res. 2020 11 06. 19(11):4496-4515. PMID: 32686424
Exposure to microplastics cause gut damage, locomotor dysfunction, epigenetic silencing, and aggravate cadmium (Cd) toxicity in Drosophila.
Zhang Y, Wolosker MB, Zhao Y, Ren H, Lemos B.
Sci Total Environ. 2020 Nov 20. 744:140979. PMID: 32721682
Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut.
Deng Y, Yan Z, Shen R, Wang M, Huang Y, Ren H, Zhang Y, Lemos B.
Environ Int. 2020 10. 143:105916. PMID: 32615348
Characterization of Cerebellum-Specific Ribosomal DNA Epigenetic Modifications in Alzheimer's Disease: Should the Cerebellum Serve as a Control Tissue After All?
Faria TC, Maldonado HL, Santos LC, DeLabio R, Payao SLM, Turecki G, Mechawar N, Santana DA, Gigek CO, Lemos B, Smith MAC, Chen ES.
Mol Neurobiol. 2020 Jun. 57(6):2563-2571. PMID: 32232768
Ribosomal DNA copy number is associated with P53 status and levels of heavy metals in gastrectomy specimens from gastric cancer patients.
Feng L, Du J, Yao C, Jiang Z, Li T, Zhang Q, Guo X, Yu M, Xia H, Shi L, Jia J, Tong Y, Ju L, Liu J, Lou J, Lemos B.
Environ Int. 2020 05. 138:105593. PMID: 32120062
Impression Cytology Is a Non-invasive and Effective Method for Ocular Cell Retrieval of Zika Infected Babies: Perspectives in OMIC Studies.
Barbosa RH, Dos Santos MLB, Silva TP, Rosa-Fernandes L, Pinto AMV, Spínola PS, Bonvicino CR, Fernandes PV, Lucena E, Palmisano G, Melo RCN, Cardoso CAA, Lemos B.
Front Mol Neurosci. 2019. 12:279. PMID: 31866819
EvoChromo: towards a synthesis of chromatin biology and evolution.
Drinnenberg IA, Berger F, Elsässer SJ, Andersen PR, Ausió J, Bickmore WA, Blackwell AR, Erwin DH, Gahan JM, Gaut BS, Harvey ZH, Henikoff S, Kao JY, Kurdistani SK, Lemos B, Levine MT, Luger K, Malik HS, Martín-Durán JM, Peichel CL, Renfree MB, Rutowicz K, Sarkies P, Schmitz RJ, Technau U, Thornton JW, Warnecke T, Wolfe KH.
Development. 2019 09 26. 146(19). PMID: 31558570
News
Uncovering a “smoking gun” of biological aging
For immediate release: February 14, 2019 Boston, MA – A newly discovered ribosomal DNA (rDNA) clock can be used to accurately determine an individual’s chronological and biological age, according to research led by Harvard T.H. Chan School of Public Health.…
Symposium gathers experts on oxidative stress and mitochondria
October 29, 2015 — Cutting-edge work on molecular mechanisms involved in the cellular response to stress was the focus at the 18th annual John B. Little Symposium, held October 23-24, 2015 at Harvard T.H. Chan School of Public Health.…
HSPH faculty members honored
November 30, 2012 -- Brendan Manning, associate professor of genetics and complex diseases, received a 2012 Senior Scholar in Aging Award from The Ellison Medical Foundation for his research on determining the genetic and metabolic relationship between the major longevity…
