Faculty Affiliate in the Department of Molecular Metabolism
Molecular Metabolism
Harvard T.H. Chan School of Public Health
My laboratory studies molecular mechanisms underlying complex gene-environment interactions in multigenic human diseases such as asthma and neurodegeneration, focusing in part on the emerging role of extracellular vesicles in disease pathogenesis, prevention, and therapeutics. Research in my laboratory is supported by multiple NIH R01 grants and a Program Project grant as well as gifts from private companies and foundations. Here are some examples of our recent work.
Park HR, Vallarino J, O'Sullivan M, Wirth C, Panganiban RA, Webb G, Shumyatcher M, Himes BE, Park JA, Christiani DC, Allen J, Lu Q.
Sci Rep. 2021 09 01. 11(1):17517. PMID: 34471210
Singh D, Marrocco A, Wohlleben W, Park HR, Diwadkar AR, Himes BE, Lu Q, Christiani DC, Demokritou P.
J Hazard Mater. 2022 01 15. 422:126771. PMID: 34391975
Wang AL, Panganiban R, Qiu W, Kho AT, Chupp G, Meyers DA, Bleecker ER, Weiss ST, Lu Q, Tantisira KG.
J Pers Med. 2021 Mar 03. 11(3). PMID: 33802355
Tiwari A, Li J, Kho AT, Sun M, Lu Q, Weiss ST, Tantisira KG, McGeachie MJ.
J Allergy Clin Immunol. 2021 06. 147(6):2181-2190. PMID: 33385444
Li J, Panganiban R, Kho AT, McGeachie MJ, Farnam L, Chase RP, Weiss ST, Lu Q, Tantisira KG.
Am J Respir Crit Care Med. 2020 07 01. 202(1):65-72. PMID: 32272022
Park HR, Sun R, Panganiban RA, Christiani DC, Lu Q.
Sci Rep. 2020 04 03. 10(1):5934. PMID: 32246005
McGeachie MJ, Sordillo JE, Dahlin A, Wang AL, Lutz SM, Tantisira KG, Panganiban R, Lu Q, Sajuthi S, Urbanek C, Kelly R, Saef B, Eng C, Oh SS, Kho AT, Croteau-Chonka DC, Weiss ST, Raby BA, Mak ACY, Rodriguez-Santana JR, Burchard EG, Seibold MA, Wu AC.
Respir Res. 2020 Jan 28. 21(1):31. PMID: 31992292
Xu R, Gopireddy RR, Wu Y, Wu L, Tao X, Shao J, Wang W, Li L, Jovanovic A, Xu B, Kenyon NJ, Lu Q, Xiang YK, Fu Q.
FASEB J. 2020 03. 34(3):3996-4008. PMID: 31960515
Yang Z, Bedugnis A, Levinson S, DiNubile M, Stossel T, Lu Q, Kobzik L.
F1000Res. 2019. 8:1860. PMID: 31824672
Zhu Z, Guo Y, Shi H, Liu CL, Panganiban RA, Chung W, O'Connor LJ, Himes BE, Gazal S, Hasegawa K, Camargo CA, Qi L, Moffatt MF, Hu FB, Lu Q, Cookson WOC, Liang L.
J Allergy Clin Immunol. 2020 02. 145(2):537-549. PMID: 31669095
March 6, 2020 – Harvard T.H. Chan School of Public Health has been awarded a five-year, multimillion-dollar federal grant to establish a Superfund Research Center to study the effects of metals and metal mixtures on cognitive health in…
Scientists are scrambling to figure out more about the vaping illness that has sickened roughly 1,300 and killed at least 29 in the U.S. Some experts are looking to see whether oily chemicals added to vaping liquids are…
For cells, effectively managing stress can be the difference between life and death. But why some cells master the art of stress management while others succumb to the pressure isn’t well understood. June 25, 2019—Researchers led by Quan…
Scientists at Harvard T.H. Chan School of Public Health demonstrated a new vesicle-based system for delivering molecular cargo into cells—a discovery that may significantly improve targeted drug delivery.
Researchers from Harvard T.H. Chan School of Public Health have identified a gene associated with lower asthma risk and its role in the disease’s progression—findings that open a new potential pathway for treatment.
