Tamarra James-Todd
Primary Faculty

Tamarra James-Todd

Mark and Catherine Winkler Associate Professor of Environmental Reproductive Epidemiology

Environmental Health

tjtodd@hsph.harvard.edu

Other Positions

Faculty Affiliate in the Department of Epidemiology

Epidemiology

Harvard T.H. Chan School of Public Health

Director, Superfund Community Engagement Core

Environmental Health

Harvard T.H. Chan School of Public Health

Instructor in Medicine

Medicine-Brigham and Women's Hospital

Harvard Medical School


Overview

As an epidemiologist, my research takes a three-way approach to studying and improving women's reproductive and long-term health by: 1) evaluating the role of environmental chemicals on adverse maternal health outcomes; 2) assessing racial/ethnic disparities in environmental chemical exposures and adverse health outcomes; and 3) developing pregnancy and postpartum interventions to improve women's chronic disease risk.

Environmental Health and Pregnancy Complications. Everyday we are exposed to hundreds of chemicals that can affect our health. Over the course of our lives, these chemicals may have differing effects that could have a greater impact on our health during certain critical and sensitive windows . Furthermore, certain populations, such as women and minorities have higher exposure levels of certain types of chemicals. My research focuses on the role of environmental endocrine disrupting chemicals in pregnancy and their effect on a number of relevant pregnancy complications.

Racial Disparities in Environmental Health. A related area of research focuses on racial/ethnic differences in environmental chemical exposures and their contribution to disparities in chronic disease risk. For this, I evaluate both non-pregnant and pregnant populations and assess sources of exposures to certain types of environmental endocrine disrupting chemicals. This work has led me to explore the role of black hair care products on risk of certain conditions, such as early age at menarche, as well as other personal care products that contain environmental endocrine disrupting chemicals.

Translational Research in Diabetes and Pregnancy. In collaboration with the Joslin Diabetes Center and Brigham and Women's Hospital, I work on identifying reproductive risk factors of subsequent development of type 2 diabetes and its complications. For this, I have assessed the effect of preterm birth on future development of type 2 diabetes in large cohort studies, including the Nurses' Health Study II and the Black Women's Health Study. I have also designed a number of interventions to reduce future risk of developing type 2 diabetes in women following a pregnancy complicated by gestational diabetes. I also conduct translational research in pregnant women with type 1 diabetes. For this work, I published one of the first studies documenting a rapid decline in blood glucose control during the postpartum period in women with type 1 diabetes, despite excellent blood glucose control during pregnancy. This work has major implications for a woman's future risk of diabetes complications.


Bibliography

Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 US Cohorts.

Welch BM, Keil AP, Buckley JP, Calafat AM, Christenbury KE, Engel SM, O'Brien KM, Rosen EM, James-Todd T, Zota AR, Ferguson KK, Alshawabkeh AN, Cordero JF, Meeker JD, Barrett ES, Bush NR, Nguyen RHN, Sathyanarayana S, Swan SH, Cantonwine DE, McElrath TF, Aalborg J, Dabelea D, Starling AP, Hauser R, Messerlian C, Zhang Y, Bradman A, Eskenazi B, Harley KG, Holland N, Bloom MS, Newman RB, Wenzel AG, Braun JM, Lanphear BP, Yolton K, Factor-Litvak P, Herbstman JB, Rauh VA, Drobnis EZ, Sparks AE, Redmon JB, Wang C, Binder AM, Michels KB, Baird DD, Jukic AMZ, Weinberg CR, Wilcox AJ, Rich DQ, Weinberger B, Padmanabhan V, Watkins DJ, Hertz-Picciotto I, Schmidt RJ.

JAMA Pediatr. 2022 09 01. 176(9):895-905. PMID: 35816333


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