Towards an integrated and life-course approach to the epidemiology of dementia.
Ma Y.
Eur J Epidemiol. 2023 07. 38(7):729-731. PMID: 37209196
Other Positions
Faculty Affiliate in the Department of Nutrition
Nutrition
Harvard T.H. Chan School of Public Health
Links
Overview
As an epidemiologist trained in preventive medicine, cardiovascular epidemiology, and aging epidemiology, Dr. Ma's research interests lie in the epidemiology and prevention of aging-related diseases, with a focus on cardiovascular disease and vascular contributions to brain aging and dementia. Dr. Ma's research work has investigated modifiable vascular risk factors and the development of effective intervention strategies for the prevention of hypertension and cardiovascular disease in prospective cohort studies, randomized trials, and health policy modeling studies. Dr. Ma's current research work aims to improve our understanding of how vascular factors contribute to brain aging and dementia using multidisciplinary approaches that integrate advanced epidemiological methods with cutting-edge neuroimaging techniques, neuropathology data, and multi-omics methods in epidemiological studies. Dr. Ma is a recipient of the American Heart Association Postdoctoral Fellowship Award, the National Academy of Medicine Healthy Longevity Catalyst Award, and the NIH K99 Pathway to Independence Award.
Bibliography
Educational Attainment and Dementia: Mediation by Mid-Life Vascular Risk Factors.
Liu C, Ma Y, Hofman A, Waziry R, Koton S, Pike JR, Windham BG, Power MC, Sharrett AR, Gottesman RF.
Ann Neurol. 2023 07. 94(1):13-26. PMID: 36966451
Age- and sex-specific modifiable risk factor profiles of dementia: evidence from the UK Biobank.
Chen H, Cao Y, Ma Y, Xu W, Zong G, Yuan C.
Eur J Epidemiol. 2023 Jan. 38(1):83-93. PMID: 36593335
Association of Long-Term Body Weight Variability With Dementia: A Prospective Study.
Chen H, Zhou T, Guo J, Ji JS, Huang L, Xu W, Zuo G, Lv X, Zheng Y, Hofman A, Ma Y, Yuan C.
J Gerontol A Biol Sci Med Sci. 2022 10 06. 77(10):2116-2122. PMID: 34908120
Daily Urinary Sodium and Potassium Excretion and Cardiovascular Risk. Reply.
Ma Y, Cook NR, Hu FB.
N Engl J Med. 2022 06 02. 386(22):e60. PMID: 35648724
APOE e4 and late-life cognition: mediation by structural brain imaging markers.
Ma Y, Sajeev G, VanderWeele TJ, Viswanathan A, Sigurdsson S, Eiriksdottir G, Aspelund T, Betensky RA, Grodstein F, Hofman A, Gudnason V, Launer L, Blacker D.
Eur J Epidemiol. 2022 Jun. 37(6):591-601. PMID: 35471691
24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk.
Ma Y, He FJ, Sun Q, Yuan C, Kieneker LM, Curhan GC, MacGregor GA, Bakker SJL, Campbell NRC, Wang M, Rimm EB, Manson JE, Willett WC, Hofman A, Gansevoort RT, Cook NR, Hu FB.
N Engl J Med. 2022 01 20. 386(3):252-263. PMID: 34767706
Visit-to-Visit Blood Pressure Variability, Neuropathology, and Cognitive Decline.
Ma Y, Blacker D, Viswanathan A, van Veluw SJ, Bos D, Vernooij MW, Hyman BT, Tzourio C, Das S, Hofman A.
Neurology. 2021 06 08. 96(23):e2812-e2823. PMID: 33903194
Lower complexity and higher variability in beat-to-beat systolic blood pressure are associated with elevated long-term risk of dementia: The Rotterdam Study.
Ma Y, Zhou J, Kavousi M, Lipsitz LA, Mattace-Raso F, Westerhof BE, Wolters FJ, Wu JW, Manor B, Ikram MK, Goudsmit J, Hofman A, Ikram MA.
Alzheimers Dement. 2021 07. 17(7):1134-1144. PMID: 33860609
Blood Pressure Variability and Dementia: A State-of-the-Art Review.
Ma Y, Tully PJ, Hofman A, Tzourio C.
Am J Hypertens. 2020 12 31. 33(12):1059-1066. PMID: 32710605
News
Drops in blood pressure linked to higher dementia risk
Orthostatic hypotension—a sudden drop in blood pressure upon standing up, resulting in dizziness—may be linked to a higher risk of developing dementia, according to a new Harvard Chan School study.
Reducing sodium and increasing potassium may lower risk of cardiovascular disease
Lower sodium and higher potassium intake is linked with lower risk of cardiovascular disease in most people, according to a study led by Harvard Chan School researchers.
