Biorxiv/in press

https://www.biorxiv.org/content/10.1101/2020.09.02.279059v3
(09/03/20; revised 04/01/21)
Dey KK, Gazal S, van de Geijn B, Kim SS, Nasser J, Engreitz JM, Price AL. Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies. bioRxiv.

 

https://www.biorxiv.org/content/10.1101/2020.09.08.288563v2
(09/09/20; revised 08/13/21)
Dey KK, Kim SS, Gazal S, Nasser J, Engreitz JM, Price AL. Integrative approaches to improve the informativeness of deep learning models for human complex diseases. bioRxiv.

 

https://biorxiv.org/cgi/content/short/2020.09.23.310748v1
(09/24/20)
Schoech AP, Weissbrod O, O’Connor LJ, Patterson N, Shi H, Reshef Y, Price AL. Negative short-range genomic autocorrelation of causal effects on human complex traits. bioRxiv.

 

https://www.medrxiv.org/content/10.1101/2021.01.19.21249483v2
(01/20/21; revised 08/20/21)
Weissbrod O*, Kanai M*, Shi H*, Gazal S, Peyrot W, Khera A, Okada Y, The Biobank Japan Project, Martin A, Finucane H, Price AL. Leveraging fine-mapping and non-European training data to improve cross-population polygenic risk scores. medrxiv. Accepted in principle, Nat Genet.

 

https://www.biorxiv.org/content/10.1101/2021.03.19.436212v2
(03/19/21; revised 11/23/2021)
Jagadeesh KA*, Dey KK*, Montoro DT, Gazal S, Engreitz JM, Xavier RJ, Price AL**, Regev A**. Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics. bioRxiv.

 

https://www.biorxiv.org/content/10.1101/2021.04.15.439975v1
(04/15/21)
Hujoel MLA, Loh PR, Neale B, Price AL. Incorporating family history of disease improves polygenic risk scores in diverse populations. bioRxiv.

 

https://www.biorxiv.org/content/10.1101/2021.05.20.445067v1
(05/21/21)
Kim SS, Jagadeesh K, Dey KK, Shen AZ, Raychaudhuri S, Kellis M, Price AL. Leveraging single-cell ATAC-seq to identify disease-critical fetal and adult brain cell types. bioRxiv.

 

https://www.biorxiv.org/content/10.1101/2021.07.22.453442v1 
(07/26/21)
Siewert-Rocks KM, Kim SS, Yao D, Shi H, Price AL. Leveraging gene co-regulation to identify gene sets enriched for disease heritability. bioRxiv. Accepted in principle, AM J Hum Genet.

 

https://www.medrxiv.org/content/10.1101/2021.08.02.21261488v1
(08/05/21)
Gazal S, Weissbrod O, Hormozdiari F, Dey K, Nasser J, Jagadeesh K, Weiner D, Shi H, Fulco C, O’Connor L, Pasaniuc B, Engreitz JM, Price AL. Combining SNP-to-gene linking strategies to pinpoint disease genes and assess disease omnigenicity. medrxiv.

 

https://www.biorxiv.org/content/10.1101/2021.09.24.461597v1
(09/28/21)
Zhang MJ*, Hou K*, Dey KK, Jagadeesh KA, Weinand K, Sajaye S, Taychameekiatchai A, Rao P, Pisco AO, Zou J, Wang B, Gandal M, Raychaudhuri S, Pasaniuc B**, Price AL**. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data. bioRxiv.