Alkes Price
Professor of Statistical Genetics
Department of Epidemiology
Department of Biostatistics
665 Huntington Avenue
Building 2, Room 211
Boston, Massachusetts 02115
Phone: 617.432.2262
aprice@hsph.harvard.edu
I am a professor in the Program in Genetic Epidemiology and Statistical Genetics in the Department of Epidemiology at HSPH, with a secondary appointment in the Department of Biostatistics. I am an associate member of the Program in Medical and Population Genetics at the Broad Institute, and a member of the Program in Quantitative Genomics at HSPH. I am the recipient of the 2017 Harvard Chan Outstanding Postdoctoral Mentor Award. Our research focuses on the development of statistical methods for uncovering the genetic basis of human disease, and on the population genetics underlying these methods. Areas of interest include functional components of heritability, common vs. rare variant architectures, and disease mapping in structured populations.
TWAS of schizophrenia and chromatin activity (Gusev et al. 2018) (slides of ASHG 2016 talk)
Heritability enrichment of specifically expressed genes paper (Finucane et al. 2018) and LD Score software (Research Highlight)
UK Biobank BOLT-LMM paper (Loh et al. 2018) and BOLT-LMM software
Heritability enrichment of molecular QTL paper (Hormozdiari et al. 2018) (slides of ASHG 2017 talk) and MaxCPP annotations
Mosaicism paper (Loh et al. 2018) (slides of ASHG 2017 talk) (News release)
ASMC paper (Palamara et al. 2018) and ASMC software (slides of ASHG 2017 talk)
Signed LD profile regression paper (Reshef et al. 2018) and software (slides of 2017 ASHG talk)
Low-frequency variant functional enrichment paper (Gazal et al. 2018) and LD Score software
LT-Fam paper (Hayeck et al. 2017) (slides of 2015 ASHG talk) and LTSOFT software
Summary statistics review paper (Pasaniuc & Price 2017)
Functional heritability of gene expression paper (Liu et al. 2017) and LD Score software
LD-dependent architecture paper (Gazal et al. 2017) (slides of GCD 2016 talk) and LD Score software
Multi-ethnic risk prediction paper (Marquez-Luna et al. 2017)
FastPCA selection paper (Galinsky et al. 2016) (slides of ASHG 2015 talk) and EIGENSOFT software
TWAS from summary statistics paper (Gusev et al. 2016) (slides of ASHG 2015 talk) (Research Highlight)
Prostate cancer functional heritability paper (Gusev et al. 2016)
Long-range phasing paper (Loh et al. 2016) and Eagle software
Reference-based phasing paper (Loh et al. 2016) and Eagle software
UK Biobank selection paper (Galinsky et al. 2016) (slides of ASHG 2016 talk) and EIGENSOFT software
BOLT-LMM paper (Loh et al. 2015) (slides of ASHG 2014 talk) and BOLT-LMM software
LD Score paper (Bulik-Sullivan et al. 2015) and LD Score software
Liability Threshold MLM paper (Hayeck et al. 2015) and LTSOFT software
Ancestry and risk prediction paper (Chen et al. 2015)
Functional heritability from summary statistics paper (Finucane et al. 2015) (slides of ASHG 2014 talk) and LD Score software
Genetic correlations from summary statistics paper (Bulik-Sullivan et al. 2015) and LD Score software
LDpred paper (Vilhjalmsson et al. 2015) and LDpred software (slides of ASHG 2015 talk)
BOLT-REML paper (Loh et al. 2015) (slides of ASHG 2015 talk) and BOLT-REML software
2VC prediction paper (Tucker et al. 2015)
Mutation rate paper (Palamara et al. 2015) (slides of ASHG 2015 talk)
Genetics of common disease review paper (Price et al. 2015)
MLM Perspective paper (Yang et al. 2014) (slides of ASHG 2013 talk) and GCTA software
Imputation from summary statistics paper (Pasaniuc et al. 2014) (slides of ASHG 2012 talk) and ImpG software
African-American selection paper (Bhatia et al. 2014)
Functional heritability paper (Gusev et al. 2014) (slides of BoG 2014 talk) (functional annotations)
Admixture-based heritability paper (Zaitlen et al. 2014) (slides of ASHG 2012 talk)
“Everything should be made as simple as possible, but no simpler” – Albert Einstein
