Alkes Price

Associate Professor of Statistical Genetics

Department of Epidemiology

Department of Biostatistics

665 Huntington Avenue
Building 2, Room 211
Boston, Massachusetts 02115
Phone: 617.432.2262
aprice@hsph.harvard.edu

I am an associate professor in the Program in Genetic Epidemiology and Statistical Genetics in the Department of Epidemiology at HSPH, with a secondary appointment in the Department of Biostatistics.  I am an associate member of the Program in Medical and Population Genetics at the Broad Institute, and a member of the Program in Quantitative Genomics at HSPH.  Our research focuses on the development of statistical methods for uncovering the genetic basis of human disease, and on the population genetics underlying these methods. Areas of interest include functional components of heritability, disease mapping in structured populations, and common vs. rare variant architectures.

LT-Fam paper (Hayeck et al. 2017) (slides of 2015 ASHG talk) and LTSOFT software

FastPCA selection paper (Galinsky et al. 2016) (slides of ASHG 2015 talk) and EIGENSOFT software
TWAS from summary statistics paper (Gusev et al. 2016) (slides of ASHG 2015 talk) (Research Highlight)
Prostate cancer functional heritability paper (Gusev et al. 2016)
Long-range phasing paper (Loh et al. 2016) and Eagle software
Reference-based phasing paper (Loh et al. 2016) and Eagle software
UK Biobank selection paper (Galinsky et al. 2016) (slides of ASHG 2016 talk) and EIGENSOFT software
Summary statistics review paper (Pasaniuc & Price 2016)

BOLT-LMM paper (Loh et al. 2015) (slides of ASHG 2014 talk) and BOLT-LMM software
LD Score paper (Bulik-Sullivan et al. 2015) and LD Score software
Liability Threshold MLM paper (Hayeck et al. 2015) and LTSOFT software
Ancestry and risk prediction paper (Chen et al. 2015)
Functional heritability from summary statistics paper (Finucane et al. 2015) (slides of ASHG 2014 talk) and LD Score software
Genetic correlations from summary statistics paper (Bulik-Sullivan et al. 2015) and LD Score software
LDpred paper (Vilhjalmsson et al. 2015) and LDpred software (slides of ASHG 2015 talk)
BOLT-REML paper (Loh et al. 2015) (slides of ASHG 2015 talk) and BOLT-REML software
2VC prediction paper (Tucker et al. 2015)
Mutation rate paper (Palamara et al. 2015) (slides of ASHG 2015 talk)
Genetics of common disease review paper (Price et al. 2015)

MLM Perspective paper (Yang et al. 2014) (slides of ASHG 2013 talk) and GCTA software
Imputation from summary statistics paper (Pasaniuc et al. 2014) (slides of ASHG 2012 talk) and ImpG software
African-American selection paper (Bhatia et al. 2014)
Functional heritability paper (Gusev et al. 2014) (slides of BoG 2014 talk) (functional annotations)
Admixture-based heritability paper (Zaitlen et al. 2014) (slides of ASHG 2012 talk)

deCODE heritability paper (Zaitlen et al. 2013) (slides of ASHG 2011 talk) (Research Highlight)
PCA SNP weights paper (Chen et al. 2013) and SNPweights software
Fst paper (Bhatia et al. 2013) (blog writeup)
Ancestry-specific TB risk paper (Chimusa et al. 2013)
Local heritability paper (Gusev et al. 2013)

 

List of all publications

“Everything should be made as simple as possible, but no simpler” – Albert Einstein