Publications

Hu CL et al.
A Population-Based Study of Genes Previously Implicated in Breast Cancer.
New England Journal of Medicine. 2021 Feb; 384(5): 440-451.
Co-Author from PGSG: Peter Kraft

 

Bonow RO et al.
2020 Focused Update of the 2017 ACC Expert Consensus Decision Pathway on the Management of Mitral Regurgitation
Journal of the American College of Cardiology. 2020 May; 75(17): 2236-2270.
Co-Author from PGSG: Alkes Price

 

Martin AR et al.
Predicting Polygenic Risk of Psychiatric Disorders.
Biological psychiatry. 2019 Jul; 86(2): 97-109.
Co-Author from PGSG: Elise Robinson

 

Hunter DJ & Bierma-Zeinstra, S.
Osteoarthritis.
Lancet. 2019 Apr; 393(10182): 1745-1759.
Co-Author from PGSG: David Hunter

 

Kichaev G et al.
Leveraging polygenic functional enrichment to improve GWAS power.
American Journal of Human Genetics. 2019 Jan; 104(1): 65-75.
Co-Author from PGSG: Alkes Price

 

Mavaddat N et al.
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
American Journal of Human Genetics. 2019 Jan; 104(1): 21-34.
Co-Author from PGSG: Peter Kraft

 

Mostafa S et al.
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease.
Nature Neuroscience. 2018 Jun; 21(6): 811-819.
Co-Author from PGSG: Lori Chibnik

 

Finucane HK et al.
Heritability enrichment of specifically expressed genes identified disease-relevant tissues and cell types
Nature Genetics. 2018 Apr; 50(4): 621-629.
Co-Author from PGSG: Alkes Price

 

Michailidou K et al.
Association analysis identifies 65 new breast cancer risk loci.
Nature. 2017 Nov; 551(7678): 92-94.
Co-Author from PGSG: Peter Kraft

 

Wang DD et al.
Plasma Ceramides, Mediterranean diet  and Incident Cardiovascular Disease in the PREDIMED Trial (Prevention con Dieta Mediterranea).
Circulation. 2017 May; 135(21): 2028-2040.
Co-Author from PGSG: Liming Liang

 

Kim ES et al.
Optimism and Cause-Specific Mortality: A Prospective Cohort Study.
American Journal of Epidemiology. 2017 Jan; 185(1): 21-29.
Co-Author from PGSG: Immaculata  De Vivo

 

Mendelson MM et al.
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.
PLoS medicine. 2017 Jan; 14(1): p.e1002215.
Co-Author from PGSG: Liming Liang

 

Bhushan R et al.
Number of Persons With Symptomatic Knee Osteoarthritis in the US: Impact of Race and Ethnicity, Age, Sex, and Obesity.
Arthritis Care & Research. 2016 Dec; 68(12): 1743-1750.
Co-Author from PGSG: David Hunter

 

Loh PR et al.
Reference-based phasing using the Haplotype Reference Consortium panel.
Nature Genetics. 2016 Nov; 48(11): 1443-1448.
Co-Author from PGSG: Alkes Price

 

Maas P et al.
Breast Cancer Risk from Modifiable and Nonmodifiable Risk Factors Among White Women in the United States.
JAMA Oncology. 2016 Oct; 2(10): 126-135.
Co-Author from PGSG: Peter Kraft

 

Gusev A et al.
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. 
Nature Communication. 2016 Apr; 7(1): 1-13.
Co-Author from PGSG: Alkes Price

 

Gusev A et al.
Integrative approaches for large-scale transcriptome-wide association studies.
Nature Genetics. 2016 Mar; 48(3): 245-252.
Co-Author from PGSG: Alkes Price

 

Galinsky KJ et al.
Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia.
American Journal of Human Genetics. 2016 Mar; 98(3): 456-472.
Co-Author from PGSG: Alkes Price

 

Gusev A et al.
Integrative approaches for large-scale transcriptome-wide association studies.
Nature Genetics. 2016 Mar; 48(3): 245-252.
Co-Author from PGSG: Alkes Price

 

Gymrek M et al.
Abundant contribution of short tandem repeats to gene expression variation in humans.
Nature Genetics. 2016 Jan; 48(1): 22-29.
Co-Author from PGSG: Alkes Price

 

Mensah-Ablorh A et al.
Meta-Analysis of Rare Variant Association Tests in Multiethnic Populations.
Genetic Epidemiology. 2016 Jan; 40(1): 57-65.
Co-Authors from PGSG: Alkes Price & Pete Kraft

 

Bulik-Sullivan B et al.
An atlas of genetic correlations across human diseases and traits.
Nature Genetics. 2015 Nov; 47(11): 1236-1241.
Co-Authors from PGSG: Alkes Price & Elise Robinson

 

Finucane HK et al.
Partitioning heritability by functional annotation using genome-wide association summary statistics.
Nature Genetics. 2015 Nov; 47(11): 1228-1235.
Co-Author from PGSG: Alkes Price

 

Vilhjálmsson BJ et al.
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
The American Journal of Human Genetics. 2015 Oct; 97(4): 576-592.
Co-Authors from PGSG: Alkes Price & Peter Kraft

 

Yan X et al.
Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers.
Cancer Cell. 2015 Oct; 28(4): 529-540.
Co-Author from PGSG: Tim Rebbeck

 

Rebbeck TR et al.
Association of Type and Location of BRCA1 and BRCA2 Mutations With Risk of Breast and Ovarian Cancer.
JAMA. 2015 Apr; 313(13): 1347-1361.
Co-Author from PGSG: Tim Rebbeck

 

Michailidou K et al.
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Nature Genetics. 2015 Apr; 47(4): 373-U127.
Co-Author from PGSG: Peter Kraft

 

Bulik-Sullivan BK et al.
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Nature Genetics. 2015 Mar; 47(3): 291-295.
Co-Author from PGSG: Alkes Price

 

Loh PR et al.
Efficient Bayesian mixed-model analysis increases association power in large cohorts.
Nature Genetics. 2015 Mar; 47(3): 284-290.
Co-Author from PGSG: Alkes Price

 

Samocha KE et al.
A framework for the interpretation of de novo mutation in human disease.
Nature Genetics. 2014 Sept; 46(9): 944-950.
Co-Author from PGSG: Elise Robinson

 

De Jager PL et al.
Alzheimer’s disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Nature Neuroscience. 2014 Aug; 17(9): 1156-1163.
Co-Author from PGSG: Lori Chibnik

 

VanderWeele TJ, Tchetgen EJT, Cornelis, M, & Kraft P.
Methodological Challenges in Medelian Randomization.
Nature Genetics. 2014 May; 25(3): 427-435.
Co-Author from PGSG: Peter Kraft

 

Hunter DJ, Schofield D, & Callander E.
The individual and socioeconomic impact of osteoarthritis.
Nature Reviews Rheumatology. 2014 Mar; 10(7): 437-441.
Co-Author from PGSG: David Hunter

 

Johnson VL and Hunter, DJ.
The epidemiology of osteoarthritis.
Best Practice & Research in Clinical Rheumatology. 2014 Feb; 28(1): 5-15.
Co-Author from PGSG: David Hunter

 

Yang J et al.
Advantages and pitfalls in the application of mixed-model association methods.
Nature Genetics. 2014 Feb; 46(2): 100-106.
Co-Author from PGSG: Alkes Price

 

Hunter DJ & Reddy, KS.
Noncommunicable Diseases.
New England and Journal of Medicine. 2013 Oct; 369(14): 1336-1343.
Co-Author from PGSG: David Hunter

 

Bradshaw EM et al.
CD33 Alzheimer’s disease locus: altered monocyte function and amyloid biology.
Nature Neuroscience. 2013 Jul; 16(7): 848-850.
Co-Author from PGSG: Lori Chibnik

 

Robinson EB et al.
Examining and interpreting the female protective effect against autistic behavior.
Proceedings of the National Academy of Sciences. 2013 Mar; 110(13): 5258-5262.
Co-Author from PGSG: Elise Robinson

 

VanderWeele TJ, Tchetgen EJT, Cornelis, M, & Kraft P.
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Blood. 2013 Jan; 121(4): 679-691.
Co-Author from PGSG: Peter Kraft