Kristopher Sarosiek's Faculty Website

Rumani Singh, PhD

Postdoctoral Fellow, 2016 – Present

Undergraduate Degree: Guru Nanak Dev University (Punjab, India)

Graduate Degree: Tsukuba University (Tsukuba, Japan)

Rumani’s Publications from the Sarosiek Laboratory:

Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX.
Rumani Singh, Stacey Yu, Marwa Osman, Zintis Inde, Cameron Fraser, Abigail Cleveland, Nicole Almanzar, Chuan Bian Lim, Gaurav Joshi, Johan Spetz, Xingping Qin, Sneh Toprani, Zachary Nagel, Matthew C Hocking, Robert A Cormack, Torunn I Yock, Jeffrey W Miller, Zhi-Min Yuan, Timothy Gershon, Kristopher Sarosiek.
Cancer Research, 2023 October 13. PDF. External.
Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy–induced toxicities.
Johan Spetz, Kiwi Florido, Cameron Fraser, Xingping Qin, Jonathan Choiniere, Stacey Yu, Rumani Singh, Max Friesen, Lee L. Rubin, Joe-Elie Salem, Javid J. Moslehi, Kristopher Sarosiek.
Science Advances, 2022 November 11. PDF. External.

Rumani Singh, Anthony Letai, Kristopher A. Sarosiek.
Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins (Review) (Featured on cover).
Nature Reviews Molecular Cell Biology, 2019 Jan 17. PDF. Pubmed.

Paula Gutierrez-Martinez, Leah Hogdal, Manavi Nagai, Miriama Kruta, Rumani Singh, Kristopher Sarosiek, Andre Nussenzweig, Isabel Beerman, Anthony Letai & Derrick J. Rossi
Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage.
Nature Cell Biology, 2018 Mar 12. Pubmed.