Publications – Harvard Chan-NIEHS Center for Environmental Health

Vaping and Lung Inflammation and Injury.

Author(s): Park JA, Crotty Alexander LE, Christiani DCJournal: Annu Rev PhysiolPMID: 34724436 February 2022

The use of electronic (e)-cigarettes was initially considered a beneficial solution to conventional cigarette smoking cessation. However, paradoxically, e-cigarette use…

Integrative omics provide biological and clinical insights into acute respiratory distress syndrome.

Author(s): Du M, Garcia JGN, Christie JD, Xin J, Cai G, Meyer NJ, Zhu Z, Yuan Q, Zhang Z, Su L, Shen S, Dong X, Li H, Hutchinson JN, Tejera P, Lin X, Wang M, Chen F, Christiani DCJournal: Intensive Care MedPMID: 34032881 February 2022

Acute respiratory distress syndrome (ARDS) is accompanied by a dysfunctional immune-inflammatory response following lung injury, including during coronavirus disease 2019…

Arsenic exposure during pregnancy and postpartum maternal glucose tolerance: evidence from Bangladesh.

Author(s): Fleisch AF, Mukherjee SK, Biswas SK, Obrycki JF, Ekramullah SM, Arman DM, Islam J, Christiani DC, Mazumdar MJournal: Environ HealthPMID: 35031057 February 2022

Arsenic exposure has been associated with gestational diabetes mellitus. However, the extent to which arsenic exposure during pregnancy is associated…

Bayesian kernel machine regression-causal mediation analysis.

Author(s): Devick KL, Bobb JF, Mazumdar M, Claus Henn B, Bellinger DC, Christiani DC, Wright RO, Williams PL, Coull BA, Valeri LJournal: Stat MedPMID: 34993981 January 2022

Greater understanding of the pathways through which an environmental mixture operates is important to design effective interventions. We present new…

Umbilical Cord Blood Metal Mixtures and Birth Size in Bangladeshi Children.

Author(s): Lee MS, Eum KD, Golam M, Quamruzzaman Q, Kile ML, Mazumdar M, Christiani DCJournal: Environ Health PerspectPMID: 33989040 May 2021

Studies have evaluated environmental exposure to toxic metals such as arsenic (As), cadmium (Cd), manganese (Mn), or lead (Pb) on…

Bayesian data fusion: Probabilistic sensitivity analysis for unmeasured confounding using informative priors based on secondary data.

Author(s): Comment L, Coull BA, Zigler C, Valeri LJournal: BiometricsPMID: 33527348 February 2021

Bayesian causal inference offers a principled approach to policy evaluation of proposed interventions on mediators or time-varying exposures. Building on…

An Unrecognized Hazard in E-Cigarette Vapor: Preliminary Quantification of Methylglyoxal Formation from Propylene Glycol in E-Cigarettes.

Author(s): Azimi P, Keshavarz Z, Lahaie Luna M, Cedeno Laurent JG, Vallarino J, Christiani DC, Allen JGJournal: Int J Environ Res Public HealthPMID: 33419122 January 2021

Up to 95% of the liquid volume in an e-cigarette consists of propylene glycol. Previous research has shown that propylene…

Association of Serum Mannose With Acute Respiratory Distress Syndrome Risk and Survival.

Author(s): Wei Y, Huang H, Zhang R, Zhu Z, Zhu Y, Lin L, Dong X, Wei L, Chen X, Liu Z, Zhao Y, Su L, Chen F, Christiani DCJournal: JAMA Netw OpenPMID: 33502483 January 2021

Acute respiratory distress syndrome (ARDS) confers high mortality risk among critically ill patients. Identification of biomarkers associated with ARDS risk…

Association between aspirin use and lung cancer incidence depends on high-frequency use, bodyweight, and age in U.S. adults.

Author(s): Dong X, He J, Lin L, Zhu Y, Chen C, Su L, Zhao Y, Zhang R, Wei Y, Chen F, Christiani DCJournal: Transl Lung Cancer ResPMID: 33569321 January 2021

Chemoprevention of cancer with aspirin is controversial as a primary prevention strategy. We sought to investigate the association between aspirin…

Stunting and lead: using causal mediation analysis to better understand how environmental lead exposure affects cognitive outcomes in children.

Author(s): Gleason KM, Valeri L, Shankar AH, Obrycki JF, Ibne Hasan MOS, Mostofa G, Quamruzzaman Q, Wright RO, Christiani DC, Bellinger DC, Mazumdar MJournal: J Neurodev DisordPMID: 33327931 December 2020

Many children in Bangladesh experience poor nutritional status and environmental lead exposure, both of which are associated with lower scores…