Author(s): Park HR, Sun R, Panganiban RA, Christiani DC, Lu Q|Journal: Sci Rep|PMID:32246005| April 2020
Arsenic (As) exposure adversely affects neurodevelopment in children. Accumulation of misfolded proteins in cells exposed to As leads to endoplasmic reticulum (ER)…
Author(s): Chen J, Zhang R, Dong X, Lin L, Zhu Y, He J, Christiani DC, Wei Y, Chen F|Journal: BMC Bioinformatics|PMID:31842743| December 2019
High-throughput technologies have brought tremendous changes to biological domains, and the resulting high-dimensional data has also posed enormous challenges to…
Author(s): Jaacks LM, Diao N, Calafat AM, Ospina M, Mazumdar M, Ibne Hasan MOS, Wright R, Quamruzzaman Q, Christiani DC|Journal: Environ Int|PMID:31675560| December 2019
Pesticide exposure during pregnancy is thought to adversely affect fetal growth, which in turn may impact child growth, but results…
Author(s): Dong X, Zhang R, He J, Lai L, Alolga RN, Shen S, Zhu Y, You D, Lin L, Chen C, Zhao Y, Duan W, Su L, Shafer A, Salama M, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Wang R, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC|Journal: Aging (Albany NY)|PMID:31434796| August 2019
Limited studies have focused on developing prognostic models with trans-omics biomarkers for early-stage lung adenocarcinoma (LUAD). We performed integrative analysis…
Author(s): North CM, MacNaughton P, Lai PS, Vallarino J, Okello S, Kakuhikire B, Tsai AC, Castro MC, Siedner MJ, Allen JG, Christiani DC|Journal: Environ Health|PMID:31429759| August 2019
Most of the global burden of pollution-related morbidity and mortality is believed to occur in resource-limited settings, where HIV serostatus…
Author(s): Obrycki JF, Lee JJ, Kapur K, Paul L, Hasan MOSI, Mia S, Quamruzzaman Q, Christiani DC, Mazumdar M|Journal: Birth Defects Res|PMID:30989821| August 2019
Mothers need a nutrient-rich diet for healthy neural tube development. Neural tube defect risk can be reduced through fortifying grain…
Author(s): Hung RJ, Spitz MR, Houlston RS, Schwartz AG, Field JK, Ying J, Li Y, Han Y, Ji X, Chen W, Wu X, Gorlov IP, Na J, de Andrade M, Liu G, Brhane Y, Diao N, Wenzlaff A, Davies MPA, Liloglou T, Timofeeva M, Muley T, Rennert H, Saliba W, Ryan BM, Bowman E, Barros-Dios JM, Pérez-Ríos M, Morgenstern H, Zienolddiny S, Skaug V, Ugolini D, Bonassi S, van der Heijden EHFM, Tardon A, Bojesen SE, Landi MT, Johansson M, Bickeböller H, Arnold S, Le Marchand L, Melander O, Andrew A, Grankvist K, Caporaso N, Teare MD, Schabath MB, Aldrich MC, Kiemeney LA, Wichmann HE, Lazarus P, Mayordomo J, Neri M, Haugen A, Zhang ZF, Ruano-Raviña A, Brenner H, Harris CC, Orlow I, Rennert G, Risch A, Brennan P, Christiani DC, Amos CI, Yang P, Gorlova OY|Journal: J Thorac Oncol|PMID:31009812| August 2019
Inherited susceptibility to lung cancer risk in never-smokers is poorly understood. The major reason for this gap in knowledge is…