***NOTICE: The IRB submission system, ESTR, will be unavailable due to maintenance from Friday, May 15 at 6:00 PM through Sunday, May 17 at 6:00 PM. Please make your plans accordingly. You will not be able to create or view submissions during this time. Application documents can be downloaded ahead of time from ESTRm or anytime from the OHRA Website. During the outage you can edit application documents in preparation for when ESTR service has been restored. Please contact your department- assigned IRB Review Specialist with any questions.

 The Office of Human Research Administration (OHRA) at Harvard Longwood Medical Area is a comprehensive administrative office designed to review, approve, assist, and oversee all human research projects conducted by Harvard T. H Chan School of Public Health, Harvard Medical School, and Harvard School of Dental Medicine faculty members and students. OHRA is the primary component of Harvard Longwood Medical Area’s Human Research Protection Program (HRPP). Within OHRA there are two major units: IRB Operations and Quality Improvement Program.