Nazneen Rahman
Head of the Division of Genetics and Epidemiology & Professor of Human Genetics at the Institute of Cancer Research
Head of the Cancer Genetics Clinical Unit at the Royal Marsden NHS Foundation Trust
Insights into the complexity of allelic function from clinical sequencing
The genotype-phenotype relationships of many disease genes are extraordinarily intricate and hint at deep uncharted complexities in gene function. Clinical phenotypic data can serve as a useful functional read-out and integration and exploration of phenotypic information in research studies should be increased. In this talk I will describe some key exemplars and outline their scientific and clinical importance.
