Galit Lahav
Professor of Systems Biology
Department of Systems Biology
Harvard Medical School
Connecting protein dynamics with drug resistance in individual cells
Many signaling molecules exhibit complex dynamical behaviors, yet little is known about how these dynamics affect cellular responses. In this talk I will focus on the dynamics of p53, a critical tumor-suppressive protein that controls genomic integrity and cell survival. I will present our work on p53 dynamics in individual cells and ask how these dynamics are shaped and affect cell fate decisions in response to chemotherapeutic drugs and irradiation.
