Nicole Soranzo, FMedSci
Senior Group Leader, Human Genetics, Wellcome Sanger Institute
Professor of Human Genetics, Department of Haematology, School of Clinical Medicine, University of Cambridge
The allelic architecture of human disease risk factors
The last two decades of genetic research have brought unprecedented insights into genetic risk factors for many complex and rare diseases. In my talk, I will discuss our work resolving the allelic architecture of quantitative risk factors for complex human diseases, including explorations of molecular intermediates and mechanisms behind observed genetic associations and explorations of polygenic risk to rare diseases.
