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mTORC1 regulates lysosome-dependent adaptive shift in intracellular lipid specie

mTORC1 in regulating the balance of intracellular lipid species between membrane phospholipids
Reciprocal effects of mTOR inhibitors on pro-survival proteins

New study from Manning Lab reveals a therapeutic strategy that combines rapamycin, which many patients are currently taking, with a BCL-2/BCL-XL
Brendan Manning receives NCI Outstanding Investigator Award

NCI’s Outstanding Investigator Award supports accomplished leaders in cancer research
New paper in Cell Reports describes first ever mouse knockout model of TBC1D7

MET researchers describe the first ever mouse knockout of TBC1D7, recapitulating the clinical manifestation of a rare human brain overgrowth disorder
Researchers Reveal the Subcellular Architecture in Liver

Parlakgül and colleagues report a detailed characterization of the subcellular architecture in liver in both healthy and obese contexts.
Training Program in Molecular Metabolism

Learn about our Training Program in Molecular Metabolism and learn about our three trainees in this program.