Social determinants of health (complex contextual factors) are considered to have a profound impact on our health, yet are not part of our health care system. Harvard Pop Center faculty member Hossein Estiri, PhD, is an author of a Perspective published in JAMIA Open that makes a case for utilizing informatics and electronic health records as a way to “…give tomorrow’s clinicians the tools and the data they need to transform the U.S. healthcare from an episodic reactive model to a preventive and proactive system.”