Research Theme
My lab integrates several scientific disciplines including molecular pathology, epidemiology, genomics, biostatistics, bioinformatics, microbiology, and immunology. We develop new research framework and models. Eg, to assess influences of the exposome and microbiome on cancer immunity, we conduct proof-of-principle studies using colorectal cancer as a disease model. We can gain novel information on the complex interactions of these elements, which can help us develop precision prevention and treatment strategies.
In essence, our research has two intersecting scientific themes. One is scientific disciplinarity and the other is a focus on specific diseases (colorectal carcinoma, colorectal polyp, colorectal adenoma, pancreatic adenocarcinoma, neuroendocrine tumor, pancreatic endocrine tumor, carcinoid tumor). Other diseases are studied on collaborative basis (esophageal carcinoma, gastro-esophageal GE junction carcinoma, Barrett’s esophagus) or on theoretical basis [non-neoplastic diseases such as obesity, inflammatory bowel diseases (IBD), ulcerative colitis, Crohn’s disease, etc]. We also deal with some diseases as exposure variables (eg., obesity, type 2 diabetes mellitus, IBD, and other immune-related diseases). Our research is interdisciplinary, transdisciplinary and multidisciplinary in nature.
We are developing several emerging fields of biomedical and population health sciences, generating novel concepts, paradigms and research frameworks. Please contact me (sogino[at]bwh.harvard.edu) if you are interested in collaborating with me in the “Molecular Pathological Epidemiology (MPE) Research” webpage.
