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HIV Working Group
April 9, 2021 @ 1:00 pm - 2:00 pm
Lara Maleyeff
Doctoral Student, Department of Biostatistics, Harvard University
“Estimating and Testing Treatment Effect Heterogeneity in Stepped Wedge Cluster Randomized Trials with Binary Outcomes”
ABSTRACT: Stepped wedge cluster randomized trials, which involve unidirectional crossover to treatment, are a vital tool in HIV research. Since clusters are followed over time with varying points of treatment initiation, these trials offer a unique opportunity to consider the interaction of calendar and exposure time trends. In this presentation, Lara will present a novel model formulation and permutation test for assessing exposure time heterogeneity in stepped wedge designs.
