Quantitative Issues in Cancer Research Working Seminar

Jeremy Simon
Senior Research Scientist, Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health

Senior Research Scientist, Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health

Abstract: I will discuss ongoing work from a personalized neoantigen vaccine clinical trial in melanoma, focusing on single-cell RNA-seq and TCR-seq data from patient samples to better understand the immune response following vaccination. I will also discuss preliminary work exploring whether single-cell chromatin accessibility (scATAC-seq) features help to define a rare but fascinating subtype of CLL.