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Quantitative Issues in Cancer Research Working Seminar
January 31 @ 4:00 pm - 5:00 pm
In Person
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Jeremy Simon
Senior Research Scientist, Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health
Senior Research Scientist, Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health
Abstract: I will discuss ongoing work from a personalized neoantigen vaccine clinical trial in melanoma, focusing on single-cell RNA-seq and TCR-seq data from patient samples to better understand the immune response following vaccination. I will also discuss preliminary work exploring whether single-cell chromatin accessibility (scATAC-seq) features help to define a rare but fascinating subtype of CLL.