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Quantitative Issues in Cancer Research Working Seminar
November 15, 2021 @ 1:00 pm - 1:50 pm
Gopal Kotecha
Doctoral Student, Department of Biostatistics, Harvard University
“Shared Control Arm Trials in the context of Glioblastoma Multiforme”
ABSTRACT: We outline clinical trial landscape of Glioblastoma Multiforme, with suggestions on how to best use the clinical information provided by this population. We review the advantages, disadvantages and barriers of various clinical trial approaches in the context of this disease. We further propose shared-control arm approaches to experimentation, and provide initial simulation data to demonstrate its benefits and trade-offs.