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Quantitative Issues in Cancer Research Working Seminar

March 20, 2023 @ 1:00 pm - 1:50 pm

Virtual In Person
03-20-2023_Cancer Working Group Seminar Flyer

Sahand Hormoz, Ph.D.
Assistant Professor of Systems Biology, Harvard Medical School, and Data Science at Dana Farber Cancer Institute

“Lineage trees and dynamics of blood cancers”

ABSTRACT: I will talk about some efforts in my lab to understand how the differentiation and proliferation dynamics of mutated blood stem cells deviate from that of healthy stem cells in certain types of blood cancers. We have been able to infer the history of expansion of cancer in individual patients by reconstructing the lineage tree of the cancer cells from the pattern of naturally occurring somatic mutations in each cell’s genome. I will also talk about how we can use synthetic biology to record each cell’s lineage history in its own DNA, circumventing the need for naturally occurring somatic mutations.


Date: March 20, 2023
Time: 1:00 pm - 1:50 pm
Calendars: Lecture / Seminar


Virtual In Person