Events Calendar

Quantitative Issues in Cancer Research Working Group Seminar

In Person

Phillip Nicol, PhD Student, Department of Biostatistics, Harvard T.H. Chan School of Public Health Estimation in Poisson log-bilinear models Abstract: The Poisson log-bilinear model, also known as GLM-PCA, is a commonly used approach for dimension reduction in single-cell RNA-seq data. Model parameters are usually estimated via maximum likelihood. However, we show that the MLE can … Continue reading "Quantitative Issues in Cancer Research Working Group Seminar"

PQG Student and Postdoc Seminar

In Person

Kodi Taraszka Research Fellow in Medicine Dana-Farber Cancer Institute COX proportional hazards Mixed Model (COXMM) accurately estimates the heritability of time-to-event traits With large biobanks connecting electronic health records with genetic sequencing, our understanding of the genetic architecture of time-to-event (TTE) traits such as age-of-onset, treatment response, and disease progression has grown. As a result, … Continue reading "PQG Student and Postdoc Seminar"

Quantitative Issues in Cancer Research Working Group Seminar

In Person

Mónica Robles Fontán, PhD Student, Department of Biostatistics, Harvard T.H. Chan School of Public Health Leveraging Record Linkage To Enhance Public Health Research Abstract: Record linkage is the task of combining records from different populations that belong to a single entity to create a new single population. This task allows researchers to take advantage of … Continue reading "Quantitative Issues in Cancer Research Working Group Seminar"

Quantitative Issues in Cancer Research Working Group Seminar

In Person

Christian Covington, PhD Student, Department of Biostatistics, Harvard T.H. Chan School of Public Health Statistical theory and the practice of data analysis: A brief and biased history Abstract: This talk gives an account of the replication crisis and how different disciplines– namely applied sciences, statistics, and theoretical computer science (TCS), have developed their own research … Continue reading "Quantitative Issues in Cancer Research Working Group Seminar"

HIV Working Group Seminar

Virtual

Mathieu Chalouni Postdoctoral Research Fellow, Harvard T.H. Chan School of Public Health, Department of Epidemiology Effect of DAA initiation and timing on the risk of liver and non-liver-related complications in persons with HIV and HCV co-infection from the HepCAUSAL collaboration Abstract: The main complication of hepatitis C virus infection is liver fibrosis, which could evolve … Continue reading "HIV Working Group Seminar"

PQG Seminar

In Person

Ruben Dries Assistant Professor, Medicine Boston University Towards Solutions for Large-Scale Multi-Modal Spatial Data Analysis In the burgeoning field of spatial biology, the integration of multi-modal spatial omics technologies presents both a formidable challenge and a tremendous opportunity for advancing clinical research and diagnostics. I will discuss the concerted efforts of our laboratory to address … Continue reading "PQG Seminar"

Quantitative Issues in Cancer Research Working Group Seminar

In Person

Elizabeth Graff, PhD Student, Department of Biostatistics, Harvard T.H. Chan School of Public Health Applications of Deep Learning for Graph-Structured Data: From Disease Spread to Social Networks Abstract: How can we apply deep learning to solve problems in modeling the spread of disease? In this talk, we will explore the components and applications of Graph … Continue reading "Quantitative Issues in Cancer Research Working Group Seminar"

Quantitative Issues in Cancer Research Working Group Seminar

In Person

Kimberly Greco, PhD Student, Department of Biostatistics, Harvard T.H. Chan School of Public Health Graph Attention Framework to Enhance Rare Disease Sub-Phenotyping from EHR Abstract: Accurately sub-phenotyping patients according to their risk for an adverse clinical outcome can significantly enhance clinical decision-making. Recent advances in patient representation learning have enabled the development of sophisticated clustering … Continue reading "Quantitative Issues in Cancer Research Working Group Seminar"

PQG Seminar

In Person

Seunggeun 'Shawn' Lee Adjunct Professor, Biostatistics University of Michigan Rare variant association analysis Rare variants significantly impact complex diseases. This presentation will first introduce SAIGE-GENE and SAIGE-GENE+, methodologies extending SAIGE … Continue reading "PQG Seminar"

Quantitative Issues in Cancer Research Working Group Seminar

In Person

Carmen B. Rodriguez, PhD Student, Department of Biostatistics, Harvard T.H. Chan School of Public Health A Bayesian Mixture Model Approach to Examining Socioeconomic Disparities in Endometrial Cancer Care in Massachusetts. Abstract: Endometrial cancer (EC) is the most common gynecologic cancer in the United States. On average, African American women have 55% higher 5-year mortality risk … Continue reading "Quantitative Issues in Cancer Research Working Group Seminar"