MET Laboratories

The Biddinger Lab

The mission of the Biddinger Laboratory is to define the molecular chain of events that link obesity, cardiovascular disease, fatty liver disease, and gallstones, leading to more effective prevention and treatment of these disorders.

The Danial Laboratory

The Danial Lab investigates the metabolic mechanisms that regulate cellular and organismal adaptation to physiologic and pathologic stress conditions.

The Hotamışlıgil Laboratory

The Hotamışlıgil Lab at the Sabri Ülker Center studies innate adaptive pathways involved in metabolic health and diseases such as obesity, diabetes, and cardiovascular disease.

The Hui Laboratory

The Hui Lab takes the in vivo flux quantification approach by integrating animal experiments, mass spectrometry, and quantitative modeling to answer fundamental questions of energy metabolism.

The Kory Laboratory

The Kory lab focuses on mitochondria, critical organelles in metabolism that generate both energy and precursors for biosynthesis.

The Mair Laboratory

The Mair Lab studies the molecular and cellular mechanisms by which animals modulate the rate at which they age in response to changes in nutrition and the environment.

The Manning Laboratory

The Manning lab is focused on defining the regulation and function of the PI3K-mTOR signaling network under both physiological and pathological settings.

The Schaffer Laboratory

The Schaffer Lab seeks a deeper understanding of disease mechanisms in order to facilitate the development of new treatments and preventative strategies to improve the lives of patients with diabetes.

The Ubellacker Laboratory

The Ubellacker Lab will leverage metabolic vulnerabilities in metastasizing cells to target and treat cancer, focusing on exploiting the lipidomic dependencies of cancer cells in the lymphatic niche.