Biostatistics Journal Club – 2/7

Biostatistics Journal Club

Journal Club: Quantifying Spatial Relationships Among Cells in ImagesFebruary 7, 2024 | 1:00-2:00pmRegister here​There is a burgeoning demand to analyze biomedical image data to quantify spatial relationships. Proximity of cell types to each other or to other features may provide clues to biological mechanisms, such as intercellular interactions. Standard point process regression models cannot easily be applied to such image data, in part because they lack physical coordinate systems. We have been adapting point process models to produce estimates of spatial clustering, i.e., the extent to which two cell types locate near (or away from) each other more (or less) than expected by chance. Jacqueline R. Starr, PhD, MS, MPH, of Brigham and Women’s Hospital has developed a meta-analytic framework to combine data across images. She will present results from oral microbial biofilm image data to illustrate the method and types of spatial metrics that can be estimated with this multivariate approach.

This event will take place virtually via Zoom


Jacqueline R. Starr, PhD, MS, MPH, Brigham and Women’s Hospital