This short course will introduce Concept and Theory, Methods and Software Tools needed to critically evaluate and conduct genetic association studies in unrelated individuals and family samples, including: multiple comparisons issues, population stratification, genome-wide association studies, genotype imputation, gene-gene and gene-environment interaction, analysis of microarray data (including gene expression, methylation data analysis, eQTL mapping). Useful software tools will be introduced during the lectures.
Section 1: December 10, 2015
1. Genome-wide association studies and genotype imputation
Instructor: Liming Liang
2. Association analysis for quantitative traits and microarray data
Instructor: Liming Liang
3. Analysis accounting for population stratification
Instructor: Anne Feng
Section 2: December 11, 2015
1. Gene-environment and gene-gene interaction
Instructor: Liming Liang
2. “Pathway” analyses
Instructor: Liming Liang
3. Estimation of genetic heritability using GWAS data
Instructor: Wonil Chung
