BPH Faculty

Andrea_Baccarelli_NewAndrea Baccarelli
Department of Environmental Health, Department of Epidemiology

Diseases: Respiratory & Cardiovascular Disease, Childhood Obesity, Fetal-growth Restriction, Cognitive Decline, Hypertension

Research: Investigates the molecular mechanisms and biomarkers that reflect reprogramming of health and disease trajectories in response to environmental exposures.


Barry_Bloom-copy1

Barry R. Bloom
Department of Immunology and Infectious Diseases

Diseases: Tuberculosis

Research: Immune response to tuberculosis.

 


Joseph_Brain-copy1Joseph Brain
Department of Environmental Health

Diseases: Environmental Lung Disease, Respiratory Infection

Research: Responses to inhaled gases, particulates, and microbes.

 


Barbara_Burleigh-copy1

Barbara Burleigh
Department of Immunology and Infectious Diseases

Diseases: Chagas’ disease

Research: Molecular basis of host cell invasion, signaling and differentiation by the human pathogen, Trypanosoma cruzi.

 


Flaminia_Catteruccia-copy1Flaminia Catteruccia
Department of Immunology and Infectious Diseases

Diseases: Malaria

Research: Reproductive biology of malaria vector, Anopheles gambiae; development of new targets for vector control.

 


David_Christiani-copy1David Christiani
Department of Environmental Health, Department of Epidemiology

Diseases: Cancer, Acute and Chronic Lung Disease, Birth Outcomes and Development, Metabolic Disorder

Research: Studying the impact of exposures to various pollutants on health and the interactions between host factors and  environmental exposures in producing acute and chronic diseases.


devivo_92x110-copy1Immaculata De Vivo
Department of Epidemiology

Diseases: Hormonal Cancers – Endometrial, Breast and Ovarian

Research: Understand mechanisms of carcinogenesis and to establish association with disease for future prevention.

 


Manoj_Duraisingh-copy2Manoj Duraisingh
Department of Immunology and Infectious Diseases

Diseases: Malaria

Research: Molecular mechanisms underlying the pathogenesis of human malaria.

 


Max_Essex-copy1Myron Essex
Department of Immunology and Infectious Diseases

Diseases: HIV

Research: Virology, immunobiology, and molecular epidemiology of HIV-1 viruses, oriented to the evolution of new viruses, both circulating recombinant forms and variants that emerge by accumulation of mutations.


FareseRobert Farese
Department of Genetics and Complex Diseases

Diseases: Obesity, Diabetes Mellitus, Fatty liver disease, Atherosclerosis

Research: How cells regulate the abundance of lipids, store lipids to buffer fluctuation in their availability and how these processes function in membrane biology and cell physiology.


Sarah_Fortune-copy1Sarah Fortune
Department of Immunology and Infectious Diseases

Diseases: Tuberculosis

Research: Secretion and pathogenesis in M. tuberculosis.

 

 


Jeffrey_Fredberg-copy1Jeffrey Fredberg
Department of Environmental Health

Diseases: Asthma

Research: Identification of the mechanical basis of airway and lung parenchymal function at the levels of organ, tissue, cell, and protein.

 


Wendy_Garrett-copy2Wendy Garrett
Department of Immunology and Infectious Diseases, Department of Genetics and Complex Diseases

Diseases: Inflammatory Bowel Disease, Colon Cancer

Research: Interplay between the innate immune system and intestinal microbial communities.


YG 1Yonatan Grad
Department of Immunology and Infectious Diseases

Diseases: Gonorrhea, Dengue virus, Respiratory Syncytial Virus, Staphylococcus aureus

Research: How pathogens evolve and spread through populations using a combination and experimental methods.


Tiffany_Horng-copy1Tiffany Horng
Department of Genetics and Complex Diseases, Department of Immunology and Infectious Diseases

Diseases: NIrp3 inflammasoome, Macrophage Biology, Chronic Inflammatory diseases, Autoinflammatory diseases

Research: Focus is on the transcriptional mechanisms that regulate inflammatory gene expression.


Gokhan_Hotamisligil-copy1Gökhan Hotamisligil
Department of Genetics and Complex Diseases, Department of Nutrition

Diseases: Diabetes, Insulin resistance, Obesity, Atherosclerosis

Research: Regulatory pathways which control energy metabolism.

 


Curtis_Huttenhower-copy1Curtis Huttenhower
Department of Biostatistics

Diseases: Human Microbiome, Computational Biology, Microbial Ecology, Inflammatory Bowel Disease, Autoimmune disorders

Research: Computational methods for systems biology using data mining in large genomic data collections.


Phyllis_Kanki-copy1Phyllis Kanki
Department of Immunology and Infectious Diseases

Diseases: HIV/AIDS

Research: Explore viral mechanisms for the differences in observed biology between HIV-2 and HIV-1.

 


Lester_Kobzik-copy1Lester Kobzik
Department of Environmental Health

Diseases: Lung Disease, Asthma, Prenatal programming for adult disease, Pneumonia, Influenza

Research: Lung macrophage differentiation and function; flow cytometry applications for respiratory cell biology.


Chi-Hao_Lee-copy1Chih-Hao Lee
Department of Genetics and Complex Diseases, Department of Nutrition

Diseases: Metabolic diseases, Obesity

Research: Nuclear lipid receptors as therapeutic targets of metabolic diseases.

 


Tun-Hou_Lee-copy1Tun-Hou Lee
Department of Immunology and Infectious Diseases

Diseases: HIV

Research: Virus-specific antigens and their association with disease manifestations, viral replication, and host-virus interactions.

 


Bernardo_Lemos-copy1Bernardo Lemos
Department of Environmental Health

Diseases: Pollution, Metals, Epigenetics

Research: Development of a functional and populational understanding of the mapping between genotypes, phenotypes, and environments.

 


Marc_Lipsitch-copy1Marc Lipsitch
Department of Epidemiology, Department of Immunology and Infectious Diseases

Diseases: Streptococcus pneumoniae, Antigenic variation, Antimicrobial resistance

Research: Effect of naturally acquired host immunity, vaccine-induced immunity & other public health interventions on population biology of pathogens


Quan-Lu-copy1Quan Lu
Department of Environmental Health, Department of Genetics and Complex Diseases

Diseases: Asthma, Diabetes, Adrenergic receptor signaling, Gene-environment interaction, Metal toxicants, RNAi screen, Non-coding RNAs

Research
: Developing and applying genomewide RNAi tools to study receptor  signaling and gene environment interactions.


Will_Mair-copy2William Mair
Department of Genetics and Complex Diseases

Diseases: Aging, Cancer, Metabolic Disease, Alzheimer’s Disease

Research: Molecular pathways underpinning the aging process.

 


Brendan_Manning-copy1Brendan Manning
Department of Genetics and Complex Diseases; Faculty Director, PhD Program in Biological Sciences in Public Health

Diseases: Cancer, Genetic Tumor Syndromes, Type-2 Diabetes, Obesity, Aging

Research
: Signaling pathways underlying tumorigenesis and metabolic diseases.

 


Matthias_Marti-copy2Matthias Marti
Department of Immunology and Infectious Diseases

Diseases: Malaria

Research: Host-pathogen interactions in malaria parasites.

 


Jay_Mitchell-copy3James Mitchell
Department of Genetics and Complex Diseases

Diseases: Surgical stress, Malaria, Cockayne Syndrome

Research: Molecular mechanisms of lifespan extension by nutritional intervention.

 


erics_lab_picture-copy1Eric Rubin
Department of Immunology and Infectious Diseases

Diseases: Tuberculosis

Research: Virulence factors of mycobacteria; acquisition of virulence determinants of Vibrio cholerae; generalized transposon mutagenesis systems for bacteria.


Frank SacksSacks-copy1
Department of Nutrition

Diseases:  Coronary Heart Disease, Hyperlipidemia, Hypertension

Research: Human lipoprotein metabolism, biochemical epidemiology involving lipoproteins and fatty acids and clinical  trials in cardiovascular disease.

 


Stephanie_Shore-copy1Stephanie Shore
Department of Environmental Health

Diseases: Asthma, Environmental Pollution, Obesity

Research: Relationship between hormones and inflammatory cytokines produced in adipose tissue and the lungs increased response to asthma triggers.

 


JosephSodroski-copy1Joseph Sodroski
Department of Immunology and Infectious Diseases

Diseases: HIV/AIDS

Research: Human immunodeficiency virus envelope glycoproteins; HIV-1 vaccine development.

 


Vishal_Vaidya-copy3Vishal Vaidya
Department of Environmental Health

Diseases: Kidney Diseases

Research: Cellular and molecular mechanisms of kidney exposure biology with a special emphasis on biomarkers, biosensors and tissue regeneration.

 


Tobias_WaltherTobias Walther
Department of Genetics and Complex Diseases

Diseases: Metabolic Diseases, Neurodegenerative Diseases

Research: How cells regulate the abundance of lipids, store lipids to buffer fluctuation in their availability and how these processes function in membrane biology and cell physiology.


Wessling-Resnick-copy1Marianne Wessling-Resnick
Department of Genetics and Complex Diseases, Department of Nutrition

Diseases: Hemochromatosis, Magnanese Neurotixcity, Iron Deficiency, Gene-environment interactions

Research: Regulation of the cellular uptake of transferrin; membrane transport of iron.


WirthDyann Wirth
Chair, Department of Immunology and Infectious Diseases; Faculty Chair, Harvard Integrated Life Sciences (HILS), Graduate School of Arts and Sciences

Diseases: Malaria

Research: Molecular genetic analysis of gene expression, malaria parasites.


Zhi-Min_Yuan-copy1Zhi-Min Yuan
Department of Genetics and Complex Diseases

Diseases: Aging, Diabetes, Cancer

Research: Elucidation of signaling mechanisms that regulate cellular stress responses; examining how stress signals affect cell behaviors in the context of cancer.