BPH Faculty

 


Barry_Bloom-copy1

Barry R. Bloom
Department of Immunology and Infectious Diseases

Diseases: Tuberculosis

Research: Immune response to tuberculosis.

 


Joseph_Brain-copy1Joseph Brain
Department of Environmental Health

Diseases: Environmental Lung Disease, Respiratory Infection

Research: Responses to inhaled gases, particulates, and microbes.

 


Douglas Brownfield
Department of Environmental Health

Diseases: Lung diseases (bronchopulmonary dysplasia, pulmonary fibrosis, chronic obstructive pulmonary disease, and emphysema)

Research: Understand how tissues are constructed during development, maintained in adulthood, and disrupted in disease.

 


Barbara_Burleigh-copy1

Barbara Burleigh
Department of Immunology and Infectious Diseases

Diseases: Chagas’ disease

Research: Molecular basis of host cell invasion, signaling and differentiation by the human pathogen, Trypanosoma cruzi.

 


Flaminia_Catteruccia-copy1Flaminia Catteruccia
Department of Immunology and Infectious Diseases

Diseases: Malaria

Research: Reproductive biology of malaria vector, Anopheles gambiae; development of new targets for vector control.

 


David_Christiani-copy1David Christiani
Department of Environmental Health, Department of Epidemiology

Diseases: Cancer, Acute and Chronic Lung Disease, Birth Outcomes and Development, Metabolic Disorder

Research: Studying the impact of exposures to various pollutants on health and the interactions between host factors and  environmental exposures in producing acute and chronic diseases.


devivo_92x110-copy1Immaculata De Vivo
Department of Epidemiology

Diseases: Hormonal Cancers – Endometrial, Breast and Ovarian

Research: Understand mechanisms of carcinogenesis and to establish association with disease for future prevention.

 


Manoj_Duraisingh-copy2Manoj Duraisingh
Department of Immunology and Infectious Diseases

Diseases: Malaria

Research: Molecular mechanisms underlying the pathogenesis of human malaria.


FareseRobert Farese
Chair, Department of Molecular Metabolism

Diseases: Obesity, Diabetes Mellitus, Fatty liver disease, Atherosclerosis

Research: How cells regulate the abundance of lipids, store lipids to buffer fluctuation in their availability and how these processes function in membrane biology and cell physiology.


Sarah_Fortune-copy1Sarah Fortune
Chair, Department of Immunology and Infectious Diseases

Diseases: Tuberculosis

Research: Secretion and pathogenesis in M. tuberculosis.

 


Jeffrey_Fredberg-copy1Jeffrey Fredberg
Department of Environmental Health

Diseases: Asthma

Research: Identification of the mechanical basis of airway and lung parenchymal function at the levels of organ, tissue, cell, and protein.

 


Wendy_Garrett-copy2Wendy Garrett
Department of Immunology and Infectious Diseases, Department of Molecular Metabolism

Diseases: Inflammatory Bowel Disease, Colon Cancer

Research: Interplay between the innate immune system and intestinal microbial communities.


Smita Gopinath
Department of Immunology and Infectious Diseases

Diseases: Genital Herpes

Research: Impact of the host microbiome on immune responses to infectious pathogens


YG 1Yonatan Grad
Department of Immunology and Infectious Diseases

Diseases: Gonorrhea, Dengue virus, Respiratory Syncytial Virus, Staphylococcus aureus

Research: How pathogens evolve and spread through populations using a combination and experimental methods.


Adam Haber
Department of Environmental Health

Diseases: Asthma and COPD

Research: Using machine learning approaches to model the disequilibrium caused by the complex interacting mixtures of inflammatory cell types in asthmatic lung tissue.


Gokhan_Hotamisligil-copy1Gökhan Hotamisligil
Department of Molecular Metabolism
Department of Nutrition

Diseases: Diabetes, Insulin resistance, Obesity, Atherosclerosis

Research: Regulatory pathways which control energy metabolism.

 


Sheng (Tony) Hui
Department of Molecular Metabolism

Diseases: Cancer cachexia, Obesity, Diabetes

Research: What is the origin of energy imbalance? Why do certain diets cause calorie surplus? Why does the body enter a state of calorie deficiency due to tumor growth?


Curtis_Huttenhower-copy1Curtis Huttenhower
Department of Biostatistics

Diseases: Human Microbiome, Computational Biology, Microbial Ecology, Inflammatory Bowel Disease, Autoimmune disorders

Research: Computational methods for systems biology using data mining in large genomic data collections.


Phyllis_Kanki-copy1Phyllis Kanki
Department of Immunology and Infectious Diseases

Diseases: HIV/AIDS

Research: Explore viral mechanisms for the differences in observed biology between HIV-2 and HIV-1.

 


C. Ronald Kahn
Department of Medicine

Diseases: Diabetes and Obesity

Research: Insulin signal transduction and mechanisms of altered signaling in diabetes and metabolic disease.


Chi-Hao_Lee-copy1Chih-Hao Lee
Department of Molecular Metabolism, Department of Nutrition

Diseases: Metabolic diseases, Obesity

Research: Nuclear lipid receptors as therapeutic targets of metabolic diseases.

 


Bernardo_Lemos-copy1Bernardo Lemos
Department of Environmental Health

Diseases: Pollution, Metals, Epigenetics

Research: Development of a functional and populational understanding of the mapping between genotypes, phenotypes, and environments.

 


Marc_Lipsitch-copy1Marc Lipsitch
Department of Epidemiology, Department of Immunology and Infectious Diseases

Diseases: Streptococcus pneumoniae, Antigenic variation, Antimicrobial resistance

Research: Effect of naturally acquired host immunity, vaccine-induced immunity & other public health interventions on population biology of pathogens


Quan-Lu-copy1Quan Lu
Department of Environmental Health, Department of Molecular Metabolism

Diseases: Asthma, Diabetes, Adrenergic receptor signaling, Gene-environment interaction, Metal toxicants, RNAi screen, Non-coding RNAs

Research
: Developing and applying genomewide RNAi tools to study receptor  signaling and gene environment interactions.


Will_Mair-copy2William Mair
Department of Molecular Metabolism

Diseases: Aging, Cancer, Metabolic Disease, Alzheimer’s Disease

Research: Molecular pathways underpinning the aging process.

 


Brendan_Manning-copy1Brendan Manning
Department of Molecular Metabolism; Faculty Director, PhD Program in Biological Sciences in Public Health

Diseases: Cancer, Genetic Tumor Syndromes, Type-2 Diabetes, Obesity, Aging

Research
: Signaling pathways underlying tumorigenesis and metabolic diseases.

 


Jay_Mitchell-copy3James Mitchell
Department of Molecular Metabolism

Diseases: Surgical stress, Cockayne Syndrome

Research: Molecular mechanisms of lifespan extension by nutritional intervention.

 


zac-nagelZachary Nagel
Department of Environmental Health

Diseases: Cancer

Research: How DNA repair affects cancer therapy efficacy and the risk of diseases associated with DNA damage.


Daniel Neafsey
Department of Immunology and Infectious Diseases

Diseases: Malaria

Research: Population, evolutionary, and functional genomics of malaria parasites and mosquito vectors.

 


Jin-Ah Park 1Jin-Ah Park
Department of Environmental Health

Diseases: Asthma and COPD

Research: Identification and characterization of biochemical and physical abnormalities of airway epithelial cells in asthma, particularly unjamming and release of extracellular vesicles.


erics_lab_picture-copy1Eric Rubin
Department of Immunology and Infectious Diseases

Diseases: Tuberculosis

Research: Virulence factors of mycobacteria; acquisition of virulence determinants of Vibrio cholerae; generalized transposon mutagenesis systems for bacteria.

 


Pardis Sabeti
Department of Immunology and Infectious Diseases

Diseases:  Infection, Inflammatory Diseases, Parasitic Diseases

Research: Creating comprehensive approaches for detecting, containing, and treating deadly infectious diseases.

 


Frank SacksSacks-copy1
Department of Nutrition

Diseases:  Coronary Heart Disease, Hyperlipidemia, Hypertension

Research: Human lipoprotein metabolism, biochemical epidemiology involving lipoproteins and fatty acids and clinical  trials in cardiovascular disease.

 


Kristopher Sarosiek
Department of Environmental Health

Diseases: Cancer, Environmental Exposures, Aging

Research: Regulation of programmed cell death (apoptosis) in health and disease.

 


RShapiro-300x300Roger Shapiro
Department of Immunology and Infectious Diseases

Diseases: HIV

Research: Prevention of mother-to-child HIV transmission (PMTCT) and the reduction of morbidity and mortality  among infants born to HIV-infected women


JosephSodroski-copy1Joseph Sodroski
Department of Immunology and Infectious Diseases

Diseases: HIV/AIDS

Research: Human immunodeficiency virus envelope glycoproteins; HIV-1 vaccine development.

 


Tobias_WaltherTobias Walther
Department of Molecular Metabolism

Diseases: Metabolic Diseases, Neurodegenerative Diseases

Research: How cells regulate the abundance of lipids, store lipids to buffer fluctuation in their availability and how these processes function in membrane biology and cell physiology.


WirthDyann Wirth
Department of Immunology and Infectious Diseases
Faculty Chair, Harvard Integrated Life Sciences (HILS), Graduate School of Arts and Sciences

Diseases: Malaria

Research: Molecular genetic analysis of gene expression, malaria parasites.


Zhi-Min_Yuan-copy1Zhi-Min Yuan
Department of Environmental Health

Diseases: Aging, Diabetes, Cancer

Research: Elucidation of signaling mechanisms that regulate cellular stress responses; examining how stress signals affect cell behaviors in the context of cancer.